TY - JOUR T1 - Chronic Pulmonary Aspergillosis: Prevalence, favouring pulmonary diseases and prognosis JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.03345-2020 SP - 2003345 AU - Maitre, Thomas AU - Cottenet, Jonathan AU - Godet,Cendrine au -Rousot,Adrien au -Abdoul Carime,Nafiz au -Ok,Vichita au -Parrot,Antoine Au -Bonniaud -Bonniaud,Philippe au -dentarin -Catherine au -Catherine au -cadranel,Cadranel,Jacques Y1 Y1- 2021/01/01/01/01/01/01 ur- Http://///////www.qdcxjkg.com/content/early/2021/01/14/13993003.03345-2020.Abstract N2-慢性肺曲霉病(CPA)是常见慢性肺疾病(CPD)患者的一种新兴疾病。尽管其患病率与流行国家的结核病(TB)有关,但低结核病发病率国家缺乏流行病学和预后数据。这项研究的目的是描述2009年至2018年在法国住院的CPA患者中的这些特征。我们估计使用法国全国行政医院数据库的住院CPA患者的患病率和死亡率。我们还评估了与CPD,胸腔干预措施和营养不良的关联。从2009年到2018年,法国的CPA住院17例290例患者,此期间的患病率越来越高。大多数患者是男性(63.5%),中位年龄为65岁,在CPA诊断,居住在农业地区和大城市中。在过去的5年中,潜在的慢性阻塞性肺疾病(COPD)和肺气肿的比例分别为44%和22%,而TB和非TB分枝杆菌(NTM)感染仅为3%。第一次住院期间,1年和5年的死亡率分别为17%,32%和45%。在多元分析中,年龄在65岁以上的患者,男性和营养不良,糖尿病或肺癌史的患者中,死亡率增加。 The risk of mortality in patients with COPD or emphysema was higher compared to those with previous mycobacterial lung infection.In France CPA is an emerging infection commonly associated with non-mycobacterial CPD. This shift in the distribution profile of underlying CPD will likely worsen CPA mortality.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Maitre has nothing to disclose.Conflict of interest: Dr. Cottenet has nothing to disclose.Conflict of interest: Cendrine Godet: received consultancy or speaker fees, travel support from Pfizer, Astellas, Gilead, MSD, SOS Oxygene, Elivie, Pulmatrix and ISIS Medical.Conflict of interest: Dr. Roussot has nothing to disclose.Conflict of interest: Dr. Abdoul Carime has nothing to disclose.Conflict of interest: Dr. Ok has nothing to disclose.Conflict of interest: Dr. Parrot has nothing to disclose.Conflict of interest: Dr. Bonniaud has nothing to disclose.Conflict of interest: Dr. Quantin has nothing to disclose.Conflict of interest: Dr. Cadranel has nothing to disclose. ER -