ty -jour t1-幼儿增长与7年的肺功能有关:一项基于人群的前瞻性研究JF-欧洲呼吸杂志JO -EUR RESSIR J DO -10.1183/13993003.00157-2020 VL -56 IS -6 SP -2000157 AU- Peralta, Gabriela P. AU - Abellan, Alicia AU - Montazeri, Parisa AU - Basterrechea, Mikel AU - Esplugues, Ana AU - González-Palacios, Sandra AU - Roda, Célina AU - Santa-Marina, Loreto AU - Sunyer, JordiAu -Vrijheid,Martine au -Casas,Maribel au -Garcia -Aymerich,Judith Y1-2020/12/01 UR -http://www.qdcxjkg.com/content.com/content/56/6/6/6/2000157.Abstract N2-先前的研究N2-相关的早期生长与后来的肺功能,但其解释受到评估儿童生长的方法的限制。我们的目的是评估幼儿增长的关联,该幼儿增长通过长达4年的体重指数(BMI)轨迹衡量,肺部功能在7年。我们包括来自西班牙基于人口基于人口的西班牙幼虫的1257名儿童。基于BMI轨迹长达4年,使用潜在的类增长分析,将幼儿增长分为五类。这些轨迹在出生率(“低”,“平均”,“更高”)和BMI增益速度(“较慢”,“加速”)方面有所不同。我们将这些轨迹与肺功能相关联(在1 s(FEV1),强迫载量(FEV1),强制生命力(FVC),FEV1/FVC和强迫呼气流量为FVC的25%–75%(FEF25-75%))在7年内,使用多变量混合回归。C.C.比平均出生率和BMI增益较慢的儿童(参考),出生率较高和加速BMI增益的儿童的FVC%PRED较高(3.3%,95%CI 1.0%–5.6%)和较低的FEV1/FVC%PRED(-1.5%,95%CI -2.9% - 0.1%)在7年。 Similar associations were observed for children with lower birth size and accelerated BMI gain. Children with lower birth size and slower BMI gain had lower FVC % pred at 7 years. No association was found for FEF25–75%.Independently of birth size, children with accelerated BMI gain in early childhood had higher lung function at 7 years but showed airflow limitation. Children with lower birth size and slower BMI gain in early childhood had lower lung function at 7 years.Independently of birth size, children with accelerated BMI gain in early childhood had higher lung function at 7 years but showed airflow limitation. Children with lower birth size and slower BMI gain in early childhood had lower lung function at 7 years. https://bit.ly/308ZDtn ER -