PT - 日刊文AU - Fukihara，君AU - Kondoh，中曾根AU - 布朗，凯文K. AU - 木村，大树AU - 片冈，狷介AU - 松田，唐泽寿AU - 山野，彦AU - 铃木淳AU - 古河，大树AU - 澄，弘光AU - 高桥，小寒AU - Johkoh，金城武AU - 田中，友纪AU - 福冈，俊雅AU - 桥本直纯AU - 长谷川义TI - 胸部CT可能UIP模式：它是足够了IPF的诊断是什么？AID - 10.1183 / 13993003.02465-2018 DP - 2020年1月1 TA - 欧洲呼吸杂志PG - 1802465 4099 - 4100 //www.qdcxjkg.com/content/early/2020/01/03/13993003.02465-2018.short - HTTP：//www.qdcxjkg.com/content/early/2020/01/03/13993003.02465-2018.full AB - 最近的研究表明，患者的特发性间质性肺炎（IIP），一个可能的普通型间质性肺炎（UIP）回顾性相比第一急性加重（AE）在IIP病人与UIP和初始胸部CT一个可能UIP图案预后和时间上胸部计算机断层扫描（CT）图案是足够的，而不histopathology.We诊断特发性肺纤维化（IPF）。一名三百六十IIP患者具有UIP模式和242有可能UIP模式进行了鉴定。可能UIP图案独立与更长的存活时间相关联（调整危险比[AHR]，0.713; 95％置信区间[95％CI]，0.536-0.950; P = 0.021）和时间第一AE（AHR，0.580; 95％CI，0.389-0.866; p = 0.008）。在一个可能的UIP模式科目谁接受外科肺活检，组织病理学UIP模式的概率为83％。多学科讨论和纵向行为纳入后，IPF的诊断，66％制成。在IPF患者，存活时间，时间到第一AE没有用CT模式相关。 Among subjects with a probable UIP pattern, compared to non-IPF patients, survival time and time to first AE were shorter in IPF patients.In conclusion, IIP patients with a probable UIP pattern on initial chest-CT had a better prognosis and longer time to first AE than those with a UIP pattern. However, when baseline data and longitudinal behaviour provided a final diagnosis of IPF, CT pattern was not associated with these outcomes. This suggests diagnostic heterogeneity among patients with a probable UIP pattern.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Fukihara has nothing to disclose.Conflict of interest: Dr. Kondoh has nothing to disclose.Conflict of interest: Dr. Brown has nothing to disclose.Conflict of interest: Dr. Kimura has nothing to disclose.Conflict of interest: Dr. Kataoka has nothing to disclose.Conflict of interest: Dr. Matsuda has nothing to disclose.Conflict of interest: Dr. Yamano has nothing to disclose.Conflict of interest: Dr. Suzuki has nothing to disclose.Conflict of interest: Dr. Furukawa has nothing to disclose.Conflict of interest: Dr. Sumikawa has nothing to disclose.Conflict of interest: Dr. Takahashi has nothing to disclose.Conflict of interest: Dr. Johkoh has nothing to disclose.Conflict of interest: Dr. Tanaka has nothing to disclose.Conflict of interest: Dr. Fukuoka has nothing to disclose.Conflict of interest: Dr. Hashimoto has nothing to disclose.Conflict of interest: Dr. Hasegawa has nothing to disclose.