% 0期刊文章% Fukihara,小君% Kondoh, Yasuhiro %一个棕色,凯文·k . %木村,名叫Tomoki % Kataoka, Kensuke %松田,Toshiaki % Yamano, Yasuhiko %铃木,Atsushi %古河道,Taiki Sumikawa %, %的高桥弘满Osamu Johkoh %, %武田中,福冈Tomonori %, %一个桥本淳弥,长谷川Naozumi %, manuscript % T可能摘要模式在胸部CT:足够的IPF诊断吗?% D J 2020% R 10.1183/13993003.02465 -2018%欧洲呼吸杂志% P 1802465 % X患者最近的研究表明,一个特发性间质性肺炎(IIP),可能平时间质性肺炎(摘要)模式在胸部计算机断层扫描(CT)足以诊断特发性肺纤维化(IPF)没有组织病理学。我们回顾性比较了初次胸部CT上UIP和可能的UIP类型的IIP患者的预后和与首次急性加重期(AE)的时间。160例IIP患者有UIP模式，242例可能有UIP模式。可能的UIP模式与较长的生存时间独立相关(调整危险比[aHR]， 0.713;95%置信区间[95% ci]， 0.536-0.950;p=0.021)和第一次AE的时间(aHR, 0.580;95%置信区间,0.389 - -0.866;p = 0.008)。在接受外科肺活组织检查的可能存在UIP模式的受试者中，组织病理学UIP模式的概率为83%。经过多学科讨论和纵向行为的纳入，诊断的IPF在66%。在IPF患者中，生存时间和首次AE的时间与CT模式无关。 Among subjects with a probable UIP pattern, compared to non-IPF patients, survival time and time to first AE were shorter in IPF patients.In conclusion, IIP patients with a probable UIP pattern on initial chest-CT had a better prognosis and longer time to first AE than those with a UIP pattern. However, when baseline data and longitudinal behaviour provided a final diagnosis of IPF, CT pattern was not associated with these outcomes. This suggests diagnostic heterogeneity among patients with a probable UIP pattern.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Fukihara has nothing to disclose.Conflict of interest: Dr. Kondoh has nothing to disclose.Conflict of interest: Dr. Brown has nothing to disclose.Conflict of interest: Dr. Kimura has nothing to disclose.Conflict of interest: Dr. Kataoka has nothing to disclose.Conflict of interest: Dr. Matsuda has nothing to disclose.Conflict of interest: Dr. Yamano has nothing to disclose.Conflict of interest: Dr. Suzuki has nothing to disclose.Conflict of interest: Dr. Furukawa has nothing to disclose.Conflict of interest: Dr. Sumikawa has nothing to disclose.Conflict of interest: Dr. Takahashi has nothing to disclose.Conflict of interest: Dr. Johkoh has nothing to disclose.Conflict of interest: Dr. Tanaka has nothing to disclose.Conflict of interest: Dr. Fukuoka has nothing to disclose.Conflict of interest: Dr. Hashimoto has nothing to disclose.Conflict of interest: Dr. Hasegawa has nothing to disclose. %U //www.qdcxjkg.com/content/erj/early/2020/01/03/13993003.02465-2018.full.pdf