TY - JOUR T1 -右室小梁质量测量作为测量的心脏MRI在疑似肺动脉高压中的诊断准确性PA5459六世- 54 - 5 63 SP - PA5459 AU -麦克唐纳,Alistair盟——约翰·克里斯AU - Garg Pankaj盟——Cogliano玛塞拉盟——Condliffe罗宾盟——野生,吉姆AU -基利,大卫AU -斯威夫特,安德鲁Y1 - 2019/09/28 UR - //www.qdcxjkg.com/content/54/suppl_63/PA5459.abstract N2 -简介:肺动脉高压(PH)患者右心室(RV)小梁团块比例较大，然而在心脏MRI (cMRI)分析中包括右心室小梁团块的价值尚不清楚。目的:探讨cMRI小梁质量测量对疑似肺动脉高压的诊断价值。方法:前瞻性队列研究144例患者在48小时内行MRI和右心导管(RHC)检查。手工绘制右心室舒张心外膜和心内膜轮廓，并应用基于像素强度的半自动阈值工具。计算小梁、压实(心外轮廓与心内膜轮廓之间)和总质量。在MRI和RHC指标之间计算Pearson相关性。利用受试者工作特性曲线研究参数的诊断准确性。诊断标准为平均肺动脉压≥25mmHg, mapp>20mmHg。右心室质量测量指标为左心室质量。结果:与右心室总质量(0.589,0.626)和压实质量(0.248,0.377)相比，小梁质量与mPAP (r=0.654)和肺血管阻力(r=0.632)的相关性更强。 With PH defined as mPAP≥25mmHg, area under the curve was significantly higher for both RV trabecular mass (AUC=0.813,p=0.002) and RV total mass (0.770,p=0.018), compared to compacted mass (0.606). With PH defined as mPAP>20, trabecular mass (0.818) was better than total mass (0.803) and compacted mass (0.703), but not significantly.Conclusion: Measurement of trabecular mass leads to increased diagnostic accuracy of cMRI in patients with suspected pulmonary hypertension.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA5459.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -