TY -的T1 -多中心的验证1公尺in sit-to-stand test in patients with COPD JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01871-2016 VL - 49 IS - 3 SP - 1601871 AU - Crook, Sarah AU - Büsching, Gilbert AU - Schultz, Konrad AU - Lehbert, Nicola AU - Jelusic, Danijel AU - Keusch, Stephan AU - Wittmann, Michael AU - Schuler, Michael AU - Radtke, Thomas AU - Frey, Martin AU - Turk, Alexander AU - Puhan, Milo A. AU - Frei, Anja Y1 - 2017/03/01 UR - //www.qdcxjkg.com/content/49/3/1601871.abstract N2 - Our aim was to comprehensively validate the 1-min sit-to-stand (STS) test in chronic obstructive pulmonary disease (COPD) patients and explore the physiological response to the test.We used data from two longitudinal studies of COPD patients who completed inpatient pulmonary rehabilitation programmes. We collected 1-min STS test, 6-min walk test (6MWT), health-related quality of life, dyspnoea and exercise cardiorespiratory data at admission and discharge. We assessed the learning effect, test–retest reliability, construct validity, responsiveness and minimal important difference of the 1-min STS test.In both studies (n=52 and n=203) the 1-min STS test was strongly correlated with the 6MWT at admission (r=0.59 and 0.64, respectively) and discharge (r=0.67 and 0.68, respectively). Intraclass correlation coefficients (95% CI) between 1-min STS tests were 0.93 (0.83–0.97) for learning effect and 0.99 (0.97–1.00) for reliability. Standardised response means (95% CI) were 0.87 (0.58–1.16) and 0.91 (0.78–1.07). The estimated minimal important difference was three repetitions. End-exercise oxygen consumption, carbon dioxide output, ventilation, breathing frequency and heart rate were similar in the 1-min STS test and 6MWT.The 1-min STS test is a reliable, valid and responsive test for measuring functional exercise capacity in COPD patients and elicited a physiological response comparable to that of the 6MWT.The 1-min STS test is a reliable, valid and responsive exercise capacity test in COPD with an MID of 3 repetitions http://ow.ly/teNx307ni0Q ER -