@article {Getahun1563,作者= {Getahun,Haileyesus和Matteelli,阿尔贝托和阿布巴卡尔,Ibrahim和阿齐兹穆罕默德阿卜杜勒和巴德利,安娜贝尔和Barreira,Draurio和Den皇家,萨斯基亚和Borroto Gutierrez的,苏珊娜玛塔和Bruchfeld,朱迪和布尔汗,Erlina和卡瓦尔坎特,索朗和Cedillos,罗兰和Chaisson,理查德和慈,辛西娅斌Eng和Chesire,露西和科贝特,伊丽莎白和达拉,马苏德和德诺姆,贾斯汀和德弗里斯,杰拉德和法尔松,丹尼斯和福特,Nathan和盖尔 - 罗维,玛格丽特和吉尔平,克里斯和吉拉迪,恩里科和围棋,取消永及Govindasamy,Darshini和D.格兰特,艾莉森和Grzemska,马乌戈热塔和哈里斯,罗斯和霍斯布鲁格JR,罗伯特C.和Ismayilov,提问者和哈拉米略埃内斯托和极乐洞,桑德拉和Kranzer,卡塔琳娜和Lienhardt,基督教和LoBue,菲利普和L {\“啊} nnroth,克努特和Marks,盖伊和孟席斯,迪克和米廖,乔瓦尼·巴蒂斯塔和莫斯卡,达维德和Mukadi,雅Diul和Mwinga,阿尔文和尼尔森,Lisa和锦织,信行和•奥尔德特-Speets,阿努克和Rangaka,Molebogeng Xheedha和雷斯,安德烈亚斯和ROTZ,Lisa和Sandgren,安德烈亚斯和萨{\〜N} {\'E} Schepisi,Monica和SCH {\“U} nemann,霍尔格J.和夏尔马Surender Kumar和Sotgiu,乔瓦尼和斯塔格,海伦R.和英镑,蒂莫西R.和塔伊布,塔玛拉和Uplekar,木孔德和van der WERF,Marieke J.和范德维德,维姆和van Kessel的,芬姆克·和van {\textquoteright}牛逼Hoog,安娜和瓦玛,周杰伦K.和Vezhnina,纳塔利娅和Voniatis,康斯坦丁和Vonk Noordegraaf - 思腾,Marije和韦尔,戴安娜和韦耶,卡琳和威尔金森,罗伯特·约翰和吉山,隆和齐薇格,让·皮埃尔·和Raviglione,马里奥},标题= {潜伏结核分枝杆菌感染的管理:世卫组织结核病低负担的国家指导方针},体积= {} 46,数= {6}页= {} 1563--1576,年份= {} 2015年,DOI = {10.1183 / 13993003.01245-2015},出版商= {欧洲呼吸协会}188bet官网地址,抽象= {潜伏性结核病感染(LTBI)的特征在于,prese的免疫应答NCE到先前获得的结核分枝杆菌感染未经活动性结核病(TB)的临床证据。Here we report evidence-based guidelines from the World Health Organization for a public health approach to the management of LTBI in high risk individuals in countries with high or middle upper income and TB incidence of \<100 per 100 000 per year. The guidelines strongly recommend systematic testing and treatment of LTBI in people living with HIV, adult and child contacts of pulmonary TB cases, patients initiating anti-tumour necrosis factor treatment, patients receiving dialysis, patients preparing for organ or haematological transplantation, and patients with silicosis. In prisoners, healthcare workers, immigrants from high TB burden countries, homeless persons and illicit drug users, systematic testing and treatment of LTBI is conditionally recommended, according to TB epidemiology and resource availability. Either commercial interferon-gamma release assays or Mantoux tuberculin skin testing could be used to test for LTBI. Chest radiography should be performed before LTBI treatment to rule out active TB disease. Recommended treatment regimens for LTBI include: 6 or 9 month isoniazid; 12 week rifapentine plus isoniazid; 3{\textendash}4 month isoniazid plus rifampicin; or 3{\textendash}4 month rifampicin alone.Guidelines on LTBI for low TB incidence countries {\textendash} essential element of the @WHO $\#$EndTB strategy and TB elimination http://ow.ly/RW8xn}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/46/6/1563}, eprint = {//www.qdcxjkg.com/content/46/6/1563.full.pdf}, journal = {European Respiratory Journal} }