Pseudomonas aeruginosabiofilms in the respiratory tract of cystic fibrosis patients
The present study was undertaken to investigate the appearance and location of Pseudomonas
aeruginosa in the cystic fibrosis (CF) lung and in sputum. Samples include preserved …
aeruginosa in the cystic fibrosis (CF) lung and in sputum. Samples include preserved …
[HTML][HTML]Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis
Mannose-binding lectin (MBL) is a key factor in innate immunity, and lung infections are the
leading cause of morbidity and mortality in cystic fibrosis (CF). Accordingly, we investigated …
leading cause of morbidity and mortality in cystic fibrosis (CF). Accordingly, we investigated …
Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa
Quorum sensing (QS) denotes a density-dependent mode of inter-bacterial communication
based on signal transmitter molecules. Active QS is present during chronic infections with the …
based on signal transmitter molecules. Active QS is present during chronic infections with the …
Occurrence of HypermutablePseudomonas aeruginosain Cystic Fibrosis Patients Is Associated with the Oxidative Stress Caused by Chronic Lung Inflammation
O Ciofu, B Riis,TPressler,HE Poulsen… - Antimicrobial agents …, 2005 - Am Soc Microbiol
Oxidative stress caused by chronic lung inflammation in patients with cystic fibrosis (CF)
and chronic lung infection with Pseudomonas aeruginosa is characterized by the reactive …
and chronic lung infection with Pseudomonas aeruginosa is characterized by the reactive …
Cystic fibrosis–an example of personalized and precision medicine
Cystic fibrosis (CF) is a severe, monogenic, autosomal recessive disease caused by mutations
in the CFTR (cystic fibrosis transmembrane regulator) gene, where disturbed chloride …
in the CFTR (cystic fibrosis transmembrane regulator) gene, where disturbed chloride …
Efficacy and safety of lumacaftor and ivacaftor in patients aged 6–11 years with cystic fibrosis homozygous for F508del-CFTR: a randomised, placebo-controlled …
…, S Junge, M Griese, D Staab,TPressler… - The Lancet Respiratory …, 2017 - Elsevier
Background Lumacaftor and ivacaftor combination treatment showed efficacy in patients
aged 12 years or older with cystic fibrosis homozygous for F508del-cystic fibrosis …
aged 12 years or older with cystic fibrosis homozygous for F508del-cystic fibrosis …
The immune response to chronicPseudomonas aeruginosalung infection in cystic fibrosis patients is predominantly of the Th2 type
Most cystic fibrosis (CF) patients with chronic Pseudomonas aeruginosa lung infection have
a persistent acute type lung inflammation dominated by polymorphonuclear neutrophils (…
a persistent acute type lung inflammation dominated by polymorphonuclear neutrophils (…
Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole …
…, HK Johansen, M Skov,TPressler… - Journal of clinical …, 2011 - Am Soc Microbiol
Respiratory tract colonization by molds in patients with cystic fibrosis (CF) were analyzed,
with particular focus on the frequency, genotype, and underlying mechanism of azole …
with particular focus on the frequency, genotype, and underlying mechanism of azole …
[HTML][HTML]Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients
HK Johansen, SM Moskowitz, O Ciofu,TPressler… - Journal of Cystic …, 2008 - Elsevier
Background Colistin resistant Pseudomonas aeruginosa have rarely been reported in cystic
fibrosis (CF) patients. Methods We performed a 17-year prospective study on colistin …
fibrosis (CF) patients. Methods We performed a 17-year prospective study on colistin …
Effect of aerosolized rhDNase (Pulmozyme®) on pulmonary colonization in patients with cystic fibrosis
B Frederiksen,TPressler, A Hansen, C Koch… - Acta …, 2006 - Wiley Online Library
Background: Aerosolized recombinant human deoxyribonuclease (rhDNase I (Pulmozyme®))
has previously been shown to increase pulmonary function and reduce exacerbations of …
has previously been shown to increase pulmonary function and reduce exacerbations of …