User profiles forStefanie M. Hauck
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Stefanie M.Hauck
Leiterin Abteilung Proteinanalytik, Helmholtz Zentrum München
Verified email at helmholtz-muenchen.de
Cited by 7826 |
三磷酸鸟苷cyclohydrolase 1 / tetrahydrobiopterin counteract ferroptosis through lipid remodeling
Ferroptosis is an iron-dependent form of regulated cell death linking iron, lipid, and glutathione
levels to degenerative processes and tumor suppression. By performing a genome-wide …
levels to degenerative processes and tumor suppression. By performing a genome-wide …
[HTML][HTML]γ-Secretase directly sheds the survival receptor BCMA from plasma cells
…, Y Chu,MSchmidt-Supprian,SMHauck… - Nature …, 2015 - nature.com
Survival of plasma cells is regulated by B-cell maturation antigen (BCMA), a membrane-bound
receptor activated by its agonist ligands BAFF and APRIL. Here we report that γ-…
receptor activated by its agonist ligands BAFF and APRIL. Here we report that γ-…
[HTML][HTML]Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry
SMHauck, J Dietter, RL Kramer, F Hofmaier… - Molecular & Cellular …, 2010 - ASBMB
Autoimmune uveitis is a blinding disease presenting with autoantibodies against eye-specific
proteins as well as autoagressive T cells invading and attacking the immune-privileged …
proteins as well as autoagressive T cells invading and attacking the immune-privileged …
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
…,MLoh,MHeinig, C Gieger,MWaldenberger… - Nature …, 2022 - nature.com
We determined the relationships between DNA sequence variation and DNA methylation
using blood samples from 3,799 Europeans and 3,195 South Asians. We identify 11,165,559 …
using blood samples from 3,799 Europeans and 3,195 South Asians. We identify 11,165,559 …
Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip
Creating in vitro models of diseases of the pancreatic ductal compartment requires a
comprehensive understanding of the developmental trajectories of pancreas-specific cell types. …
comprehensive understanding of the developmental trajectories of pancreas-specific cell types. …
Differential protein profiling of primary versus immortalized human RPE cells identifies expression patterns associated with cytoskeletal remodeling and cell survival
CS Alge,SMHauck,SG Priglinger… - Journal of proteome …, 2006 - ACS Publications
Functional research of retinal pigment epithelium (RPE) most often relies on utilization of
RPE-derived cell lines in vitro. However, no studies about similarities and differences of the …
RPE-derived cell lines in vitro. However, no studies about similarities and differences of the …
Direct comparison of MS‐based label‐free and SILAC quantitative proteome profiling strategies in primary retinalMüller cells
To better understand the involvement of retinal Müller glial (RMG) cells in retinal diseases,
we phenotyped primary porcine RMGs in dependence of cultivation time using different …
we phenotyped primary porcine RMGs in dependence of cultivation time using different …
Calpain is activated in degenerating photoreceptors in the rd1 mouse
The retinal degeneration (rd)1 mouse displays an inherited retinal degeneration and
therefore allows studies of the molecular mechanisms behind the blinding disease retinitis …
therefore allows studies of the molecular mechanisms behind the blinding disease retinitis …
Excessive local host-graft connectivity in aging and amyloid-loaded brain
…,MThorwirth, Y Zarb,KK Conzelmann,SMHauck… - Science …, 2022 - science.org
Transplantation is a clinically relevant approach for brain repair, but much remains to be
understood about influences of the disease environment on transplant connectivity. To explore …
understood about influences of the disease environment on transplant connectivity. To explore …
[HTML][HTML]ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations
E Kortvely,SMHauck, G Duetsch… - … & visual science, 2010 - arvojournals.org
Purpose.: SNPs in chromosomal region 10q26 harboring PLEKHA1, ARMS2, and Htra1
showed the strongest association with age-related macular degeneration. Recent evidence …
showed the strongest association with age-related macular degeneration. Recent evidence …