Characterization of the inflammatory response to severe COVID-19 illness

…, ME O'Brien, RK Morgan,RWCostello… - American journal of …, 2020 - atsjournals.org
理由是:冠状病毒迪sease (COVID-19) is a global threat to health. Its inflammatory
characteristics are incompletely understood. Objectives: To define the cytokine profile of COVID-…

Use of Sniff nasal-inspiratory force to predict survival in amyotrophic lateral sclerosis

…,R Conroy,O Hardiman,RWCostello- American journal of …, 2005 - atsjournals.org
… Correspondence and requests for reprints should be addressed toRichard W.Costello,
Department of Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, …

Objective assessment of adherence to inhalers by patients with chronic obstructive pulmonary disease

…,F Doyle,F Boland,RB Reilly,RWCostello- American journal of …, 2017 - atsjournals.org
… Correspondence and requests for reprints should be addressed toRichard W.Costello,
MD, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland. E-mail: [email …

Lung mechanics and dyspnea during exacerbations of chronic obstructive pulmonary disease

NJ Stevenson, PP Walker,RWCostello… - American journal of …, 2005 - atsjournals.org
Rationale: Exacerbation of chronic obstructive pulmonary disease commonly causes
hospitalization. The change in lung mechanics during exacerbation and its relationship to …

[HTML][HTML]Short term and long term effects of pulmonary rehabilitation on physical activity in COPD

…, NM McCormack,MA Spruit,RWCostello- Respiratory …, 2012 - Elsevier
… of interestRichard Costelloreports no other conflicts of interest.Richard Costellois the
guarantor of the data in this paper. …Richard Costellois the guarantor of the data in this paper. …

Localization of eosinophils to airway nerves and effect on neuronal M2 muscarinic receptor function

RWCostello, BH Schofield… - … of Physiology-Lung …, 1997 - journals.physiology.org
Neuronal M2 muscarinic receptors inhibit acetylcholine release from pulmonary parasympathetic
nerves but are dysfunctional in antigen-challenged animals and asthmatics. Deletion of …

A randomised clinical trial of feedback on inhaler adherence and technique in patients with severe uncontrolled asthma

…,RB Reilly,F Doyle,RWCostello- European …, 2018 - Eur Respiratory Soc
In severe asthma, poor control could reflect issues of medication adherence or inhaler technique,
or that the condition is refractory. This study aimed to determine if an intervention with (…

Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma

…,P Bradding,M Ennis,A Zholos,RWCostello… - Journal of Allergy and …, 2014 - Elsevier
Background The airway epithelium is exposed to a range of physical and chemical irritants in
the environment that are known to trigger asthma. Transient receptor potential (TRP) cation …

[HTML][HTML]Extending a home from hospital care programme for COPD exacerbations to include pulmonary rehabilitation

N Murphy, C Bell,RWCostello- Respiratory medicine, 2005 - Elsevier
The principals of rehabilitation medicine are to prevent muscle atrophy and improve mobility.
Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with …

Impact of cough across different chronic respiratory diseases: comparison of two cough-specific health-related quality of life questionnaires

…, E Murtagh, J Ramsey, J MacMahon,RWCostello… - Chest, 2008 - Elsevier
Background Cough is a prominent symptom across a range of common chronic respiratory
diseases and impacts considerably on patient health status. Methods We undertook a cross-…