Risk assessment of chronic lung allograft dysfunction phenotypes: Validation and proposed refinement of the 2019 International Society for Heart and Lung …

…,M Kawashima, A Takahagi, E Fuchs, RGhany… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND Chronic lung allograft dysfunction (CLAD) is a heterogeneous condition.
Characterization of CLAD phenotypes is essential to enhance the understanding of …

The impact of first untreated subclinical minimal acute rejection on risk for chronic lung allograft dysfunction or death after lung transplantation

L Levy, E Huszti,J Tikkanen, RGhany… - American Journal of …, 2020 - Wiley Online Library
Acute cellular rejection ( ACR ) is a significant risk factor for chronic lung allograft dysfunction
( CLAD ). Although clinically manifest and higher grade (≥A2) ACR is generally treated …

Diffusing capacity of the lung for carbon monoxide: association with long-term outcomes after lung transplantation in a 20-year longitudinal study

DR Darley, J Ma, E Huszti, RGhany… - European …, 2022 - Eur Respiratory Soc
Rationale The diffusing capacity of the lung for carbon monoxide corrected for haemoglobin
(D LCOcor ) measures gas movement across the alveolar–capillary interface. We …

Long‐term outcomes of sensitized lung transplant recipients after peri‐operative desensitization

…,C Patriquin,M Cypel,D Barth, RGhany… - American Journal of …, 2021 - Wiley Online Library
The Toronto Lung Transplant Program has been using a peri‐operative desensitization regimen
of plasma exchange, intravenous immune globulin, and antithymocyte globulin in order …

Bronchoalveolar bile acid and inflammatory markers to identify high-risk lung transplant recipients with reflux and microaspiration

…, AT Sage,S Azad, R Zamel, RGhany… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND Gastroesophageal reflux disease (GERD) is a risk factor for chronic lung
allograft dysfunction. Bile acids—putative markers of gastric microaspiration—and …

Predicting donor lung acceptance for transplant during ex vivo lung perfusion: The EX vivo lung PerfusIon pREdiction (EXPIRE)

…,M Liu, JC Yeung, J Valero, RGhany… - American Journal of …, 2021 - Wiley Online Library
Ex vivo lung perfusion (EVLP) has being increasingly used for the pretransplant assessment
dono扩展量的标准r lungs. Mathematical models to predict lung acceptance during …

Bronchoalveolar lavage cytokine-based risk stratification of minimal acute rejection in clinically stable lung transplant recipients

L Levy, E Huszti, M Ahmed, RGhany, S Hunter… - The Journal of Heart and …, 2021 - Elsevier
Background Acute cellular rejection (ACR) remains the most significant risk factor for chronic
lung allograft dysfunction (CLAD). While clinically significant or higher-grade (≥A2) ACR is …

The accuracy of forced vital capacity for diagnosing restrictive allograft syndrome and mixed phenotype of chronic lung allograft dysfunction

…, A Takahagi,S Moshkelgosha, RGhany… - European …, 2021 - Eur Respiratory Soc
… Liran Levy, Ella Huszti, Gregory Berra, Benjamin Renaud-Picard, Mitsuaki Kawashima,
Akihiro Takahagi, Sajad Moshkelgosha,Rasheed Ghany, Eyal Fuchs, Chung-Wai Chow, Shaf …

Significance of phenotype change after chronic lung allograft dysfunction onset

…,M Kawashima, A Takahagi, RGhany… - Transplant …, 2021 - Wiley Online Library
Definitions for chronic lung allograft dysfunction (CLAD) phenotypes were recently revised (2019
ISHLT consensus). Post‐CLAD onset phenotype transition may occur as a result of …

The Impact of Inadequate (“AX”) Transbronchial Biopsies on Post–lung Transplant CLAD or Death

L Levy, E Huszti,P Pal,J Tikkanen, RGhany… - …, 2021 - journals.lww.com
Background. Procuring a good quality transbronchial-biopsy sample is essential for
diagnosing acute cellular rejection after lung transplantation (LT). Insufficient transbronchial-biopsy …