Background It is unknown whether genetic factors predispose patients to idiopathic
pancreatitis. In patients with cystic fibrosis, mutations of the cystic fibrosis transmembrane …

Primary ciliary dyskinesia (PCD) is a genetic disease characterized by abnormalities in
ciliary structure/function. We hypothesized that the major clinical and biologic phenotypic …

Primary ciliary dyskinesia (PCD, MIM 242650) is characterized by recurrent infections of the
respiratory tract due to reduced mucociliary clearance and by sperm immobility. Half of the …

Background— Primary ciliary dyskinesia (PCD) is a recessive genetic disorder that is
characterized by sinopulmonary disease and reflects abnormal ciliary structure and function. Situs …

Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can cause
chronic pulmonary infection, particularly in individuals with pre-existing inflammatory lung …

Lung infections with Mycobacterium abscessus, a species of multidrug-resistant nontuberculous
mycobacteria, are emerging as an important global threat to individuals with cystic …

Background & Aims: Nonalcoholic chronic pancreatitis is usually idiopathic and often
associated with cystic fibrosis gene (CFTR) mutations. It is unknown whether pancreatitis risk …

Background Although nontuberculous mycobacteria (NTM) are recognized pathogens in
cystic fibrosis (CF), associations with clinical outcomes remain unclear. Methods …

Rationale: Primary ciliary dyskinesia (PCD) is characterized by recurrent airway infections
and randomization of left–right body asymmetry. To date, autosomal recessive mutations have …

Cystic fibrosis is a genetic disease that is associated with abnormal sweat electrolytes, sino-pulmonary
disease, exocrine pancreatic insufficiency, and male infertility. Insights into …