Background Malignant pleural effusion (MPE) causes debilitating breathlessness and
predicting survival is challenging. This study aimed to obtain contemporary data on survival
by underlying tumour type in patients with MPE, identify prognostic indicators of overall …

Primary spontaneous pneumothorax (PSP) affects young healthy people with a significant
recurrence rate. Recent advances in treatment have been variably implemented in clinical
practice. This statement reviews the latest developments and concepts to improve clinical …

这re are substantial differences in international guidelines for the management of
气胸和临床实践中的地理变异。这些差异
部分地由缺乏高质量证据驱动。诊断进展......

Pneumothorax describes the presence of gas within the pleural space, between the lung
and the chest wall. It remains a globally important health problem, with considerable
associated morbidity and healthcare costs. Without prompt management pneumothorax can …

Rationale: Intrapleural therapy with a combination of tissue plasminogen activator (tPA) 10
mg and DNase 5 mg administered twice daily has been shown in randomized and open-
label studies to successfully manage over 90% of patients with pleural infection without …

Background Video-assisted thoracoscopic surgery (VATS) is an increasingly common
treatment for recurrent or persistent primary spontaneous pneumothorax (PSP). Surgery
usually involves diffuse treatment of the pleura and possible targeted therapy to areas of …

Secondary spontaneous pneumothorax (SSP) is traditionally managed with an intercostal
chest tube attached to an underwater seal. We investigated whether use of a one-way flutter
valve shortened patients' length of stay (LoS). This open-label randomised controlled trial …

这evidence base concerning the management of benign pleural effusions has lagged
behind that of malignant pleural effusions in which recent randomised trials are now
informing current clinical practice and international guidelines. The causes of benign pleural …

Bacterial pleural infection requires prompt identification to enable appropriate investigation
and treatment. In contrast to commonly used biomarkers such as C-reactive protein (CRP)
and white cell count (WCC), which can be raised due to non-infective inflammatory …

Rationale: Evaluation of a pleural effusion has historically focused on establishing a single
病因。胸腔流体可以通过多种病理生理过程积累。这
prevalence of multiple causes for pleural effusions has not been established. The …