In subjects with chronic obstructive pulmonary disease (COPD), hyperpolarized xenon-129
( 129 Xe) magnetic resonance imaging (MRI) reveals significantly greater ventilation defects …

Pulmonary magnetic resonance imaging using hyperpolarised 129 Xe gas (XeMRI) can
quantify ventilation inhomogeneity by measuring the percentage of unventilated lung volume (…

Methods This study was approved by the research ethics board at the Hospital for Sick
Children (research ethics board approval no. 1000048243).(Clinical trial registered with www. …

Conventional pulmonary function tests appear normal in early cystic fibrosis (CF) lung disease.
Therefore, new diagnostic approaches are required that can detect CF lung disease in …

Background The ventilation defect percent (VDP), measured from hyperpolarized (HP) 129
Xe magnetic resonance imaging (MRI), is sensitive to functional changes in cystic fibrosis (CF…

Purpose To assess the feasibility of hyperpolarized 129 Xe multiple‐breath washout MRI in
pediatric cystic fibrosis (CF) participants with preserved lung function. Fractional ventilation (r)…

A chronic obstructive pulmonary disease (COPD) exsmoker underwent pulmonary function
tests and hyperpolarized helium‐3 ( 3 He) magnetic resonance imaging (MRI) serially over 4 …

PURPOSE: We evaluated a handheld oscillating positive expiratory pressure (oPEP) device
(Aerobika®, Trudell Medical International, Canada) that combines positive expiratory …

Results-measurements (three for LCI and two for VDP) obtained within a few minutes of each
other. A good correlation (r= 0.79) between LCI and VDP was observed. These results also …

1. Stahl M, Wielp ütz MO, Graeber SY, Joachim C, Sommerburg O, Kauczor HU, et al.
Comparison of lung clearance index and magnetic resonance imaging for assessment of lung …