Age-specific distribution of plasma amino acid concentrations in a healthy pediatric population

N Lepage, NMcDonald, L Dallaire… - Clinical …, 1997 - academic.oup.com
Reference values were determined for 23 plasma free amino acids from measurements
done in 148 healthy children ranging from 0 to 18 years of age. Amino acid analysis was …

Inhaled hypertonic saline in preschool children with cystic fibrosis (SHIP): a multicentre, randomised, double-blind, placebo-controlled trial

…, M Siegel, S Isaac, R Jensen, J Au, NMcDonald… - The Lancet Respiratory …, 2019 - Elsevier
Background Inhaled hypertonic saline enhances mucociliary clearance, improves lung
function, and reduces pulmonary exacerbations in people with cystic fibrosis older than age 6 …

Multiple kernel multivariate performance learning using cutting plane algorithm

…, H Wang,Y Zhou, NMcDonald- 2015 IEEE International …, 2015 - ieeexplore.ieee.org
In this paper, we propose a multi-kernel classifier learning algorithm to optimize a given
nonlinear and nonsmoonth multivariate classifier performance measure. Moreover, to solve the …

Hyperpolarised 129Xe magnetic resonance imaging to monitor treatment response in children with cystic fibrosis

JH Rayment,MJ Couch, NMcDonald… - European …, 2019 - Eur Respiratory Soc
Pulmonary magnetic resonance imaging using hyperpolarised 129 Xe gas (XeMRI) can
quantify ventilation inhomogeneity by measuring the percentage of unventilated lung volume (…

Changes in airway inflammation during pulmonary exacerbations in patients with cystic fibrosis and primary ciliary dyskinesia

…, V Waters,M Klingel, NMcDonald… - European …, 2016 - Eur Respiratory Soc
Lung disease in patients with both primary ciliary dyskinesia (PCD) or cystic fibrosis (CF) is
associated with impaired mucociliary clearance; however, clinical outcomes are typically …

Lung clearance index to track acute respiratory events in school-age children with cystic fibrosis

…, M Shaw, R Jensen, NMcDonald… - American Journal of …, 2021 - atsjournals.org
Rationale: The lung clearance index (LCI) is responsive to acute respiratory events in
preschool children with cystic fibrosis (CF), but its utility to identify and manage these events in …

Determinants of lung disease progression measured by lung clearance index in children with cystic fibrosis

…, J Guido, S Jara, L France, NMcDonald… - European …, 2021 - Eur Respiratory Soc
The lung clearance index (LCI) measured by the multiple breath washout (MBW) test is
sensitive to early lung disease in children with cystic fibrosis. While LCI worsens during the …

Comparison of combined heart‒liver vs heart-only transplantation in pediatric and young adult Fontan recipients

…, R Bensen, M Navaratnam, NMcDonald… - The Journal of Heart and …, 2021 - Elsevier
BACKGROUND Indications for a heart‒liver transplantation (HLT) for Fontan recipients are
not well defined. We compared listing characteristics, post-operative complications, and post-…

Changes in magnetic resonance imaging scores and ventilation inhomogeneity in children with cystic fibrosis pulmonary exacerbations

…, P Ciet,R Amin, NMcDonald2017 -欧盟欧洲……,r Respiratory Soc
… Hartmut Grasemann, Pierluigi Ciet, Reshma Amin,Nancy McDonald, Michelle Klingel,
Harm AWM Tiddens, Felix Ratjen, Lars Grosse-Wortmann …McDonaldA, …

Healthy hearts via live videoconferencing: an exercise and diet intervention in pediatric heart transplant recipients

…, KJ Stauffer, J Brabender, NMcDonald… - Journal of the …, 2020 - Am Heart Assoc
Background Pediatric heart transplant recipients have high‐risk cardiovascular profiles that
can affect their long‐term outcomes; however, promoting exercise and healthy diet has not …