越来越多的证据了ustrates a fundamental role for mitochondria in lung alveolar type
2 epithelial cell (AEC2) dysfunction in the pathogenesis of idiopathic pulmonary fibrosis. …

Hepatocyte growth factor (HGF) plays an important role in angiogenesis, cell proliferation,
antifibrosis, and antiapoptosis. Moreover, recent studies have highlighted the …

Allergic inflammation in the airway is generally considered a Th2-type immune response.
However, Th17-type immune responses also play important roles in this process, especially in …

Allergic airway inflammation is generally considered a Th2-type immune response. Recent
studies, however, demonstrated that Th17-type immune responses also play important roles …

In patients requiring ventilator support, mechanical ventilation (MV) may induce acute lung
injury (ventilator-induced lung injury [VILI]). VILI is associated with substantial morbidity and …

Acute kidney injury (AKI) is a serious problem in critically ill patients of intensive care units. It
has been reported previously that AKI can induce acute lung injury (ALI), as well as cause …

Renal fibrosis is a common pathogenic response to injury in chronic kidney disease (CKD).
The receptor-interacting protein kinase-3 (RIPK3), a regulator of necroptosis, has been …

Allergic inflammation in the airway is generally considered a Th2-type immune response.
However, recent studies demonstrated that Th1- and Th17-type immune responses also play …

It is currently not understood whether cigarette smoke exposure facilitates sensitisation to
self-antigens and whether ensuing auto-reactive T cells drive chronic obstructive pulmonary …

We reported that Pla2g5-null mice lacking group V secretory phospholipase A 2 (gV-sPLA 2
) showed reduced eosinophilic pulmonary inflammation and Th2 cytokine generation when …