Airway inflammation is considered to be the primary component contributing to the
heterogeneity and severity of airway disorders. Therapeutic efficacies of diverse novel biologics …

Asthma and autoimmune diseases both result from a dysregulated immune system, and have
been conventionally considered to have mutually exclusive pathogenesis. Autoimmunity is …

Eosinophils are an enigmatic white blood cell whose immune functions are still under intense
investigation. Classically, the eosinophil was considered to fulfill a protective role against …

Rationale: Clinical benefits of fixed-dose 100-mg subcutaneous (SC) mepolizumab in
prednisone-dependent patients are modest when sputum eosinophilia is not adequately controlled…

Counting of red blood cells (rbc) in blood cell images is very important to detect as well as to
follow the process of treatment of many diseases like anaemia, leukaemia etc. However, …

There is paucity of evidence assessing immune responses to COVID‐19 in severe
asthmatics treated with biologics. Recent guidelines recommend continuing these agents (as …

Background In clinical trials, the two anti-interleukin (IL)-5 monoclonal antibodies (mAbs:
mepolizumab and reslizumab) approved to treat severe eosinophilic asthma reduce …

Background The persistence of eosinophils in sputum despite high doses of corticosteroids
indicates disease severity in asthmatic patients. Chronic inflamed airways can lose tolerance …

8. Silverberg JI, Kleiman E, Lev-Tov H, Silverberg NB, Durkin HG, Joks R, et al. Association
between obesity and atopic dermatitis in childhood: a case-control study. J Allergy Clin …

Background Thymic stromal lymphopoietin (TSLP) and IL-33 are considered important initiators
of type 2 immunity. In asthmatic patients allergic inflammatory responses are associated …