Comparative genomics: the bacterial pan-genome
细菌通用电气nome sequencing has become so easy and accessible that the genomes of
multiple strains of more and more individual species have been and will be generated. These …
multiple strains of more and more individual species have been and will be generated. These …
[HTML][HTML]DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae
Here we determine the complete genomic sequence of the Gram negative, γ-Proteobacterium
Vibrio cholerae El Tor N16961 to be 4,033,460 base pairs (bp). The genome consists of …
Vibrio cholerae El Tor N16961 to be 4,033,460 base pairs (bp). The genome consists of …
Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial “pan-genome”
HTettelin, V Masignani… - Proceedings of the …, 2005 - National Acad Sciences
The development of efficient and inexpensive genome sequencing methods has revolutionized
the study of human bacterial pathogens and improved vaccine design. Unfortunately, the …
the study of human bacterial pathogens and improved vaccine design. Unfortunately, the …
Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing
…, E Hundt, B Knapp, E Blair, T Mason, HTettelin… - Science, 2000 - science.org
Neisseria meningitidis is a major cause of bacterial septicemia and meningitis. Sequence
variation of surface-exposed proteins and cross-reactivity of the serogroup B capsular …
variation of surface-exposed proteins and cross-reactivity of the serogroup B capsular …
Complete Genome Sequence ofNeisseria meningitidisSerogroup B Strain MC58
HTettelin,NJ Saunders, J Heidelberg, AC Jeffries… - Science, 2000 - science.org
The 2,272,351–base pair genome of Neisseria meningitidis strain MC58 (serogroup B), a
causative agent of meningitis and septicemia, contains 2158 predicted coding regions, 1158 (…
causative agent of meningitis and septicemia, contains 2158 predicted coding regions, 1158 (…
Complete Genome Sequence of a Virulent Isolate ofStreptococcus pneumoniae
The 2,160,837–base pair genome sequence of an isolate of Streptococcus pneumoniae, a
Gram-positive pathogen that causes pneumonia, bacteremia, meningitis, and otitis media, …
Gram-positive pathogen that causes pneumonia, bacteremia, meningitis, and otitis media, …
Genome Sequence of Avery's Virulent Serotype 2 Strain D39 ofStreptococcus pneumoniaeand Comparison with That of Unencapsulated Laboratory Strain R6
…, TM Davidsen,KJ Wayne, HTettelin… - Journal of …, 2007 - Am Soc Microbiol
Streptococcus pneumoniae (pneumococcus) is a leading human respiratory pathogen that
causes a variety of serious mucosal and invasive diseases. D39 is an historically important …
causes a variety of serious mucosal and invasive diseases. D39 is an historically important …
[HTML][HTML]Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species
Streptococcus pneumoniae is one of the most important causes of microbial diseases in
humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed and compared …
humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed and compared …
Life with 6000 genes
…,HW Mewes, Y Murakami, P Philippsen, HTettelin… - Science, 1996 - science.org
The genome of the yeast Saccharomyces cerevisiae has been completely sequenced
through a worldwide collaboration. The sequence of 12,068 kilobases defines 5885 potential …
through a worldwide collaboration. The sequence of 12,068 kilobases defines 5885 potential …
The microbial pan-genome
A decade after the beginning of the genomic era, the question of how genomics can describe
a bacterial species has not been fully addressed. Experimental data have shown that in …
a bacterial species has not been fully addressed. Experimental data have shown that in …