Aluminum-based adjuvants (aluminum salts or alum) are widely used in human vaccination,
although their mechanisms of action are poorly understood. Here we report that, in mice, …

Eosinophils are typically considered to be specialized effector cells that are recruited to the
tissues as a result of T helper type 2 (Th2) cell responses associated with helminth infections …

Targeting NETosis alleviates type-2 immunopathology induced by rhinovirus infection in a
mouse model of airway hypersensitivity, and correlative data suggest that a similar …

For a long time, investigations about the lung myeloid compartment have been mainly
limited to the macrophages located within the airways, that is, the well-known alveolar …

Lung macrophages have mostly been studied considering only their most accessible and
well-defined representative, the alveolar macrophage (AM). In contrast, the identity and …

The respiratory tract is continuously exposed to both innocuous airborne antigens and
immunostimulatory molecules of microbial origin, such as LPS. At low concentrations, airborne …

…Bureaujointly directed this work and are co–last authors. …Bureaujointly directed this
work and are co–last authors. …Bureaujointly directed this work and are co–last authors. …

The conditions leading to the activation/differentiation of T-helper (Th) cells dedicated for B-cell
antibody production are still poorly characterized. We now demonstrate that interleukin-6 …

Nicotinamide phosphoribosyl transferase (Nampt)/pre-B cell colony-enhancing factor (PBEF)/visfatin
is a protein displaying multiple functional properties. Originally described as a …

Background Asthma is classified according to severity and inflammatory phenotype and is
likely to be distinguished by specific microRNA (miRNA) expression profiles. Objective We …