[HTML][HTML]Prenatal nicotine increases pulmonary α7 nicotinic receptor expression and alters fetal lung development in monkeys
…, JA Whitsett, J Lindstrom,ERSpindel- The Journal of …, 1999 - Am Soc Clin Investig
It is well established that maternal smoking during pregnancy is a leading preventable
低的原因birth weight and prematurity. Less appreciated is that maternal smoking during …
低的原因birth weight and prematurity. Less appreciated is that maternal smoking during …
Acetylcholine is synthesized by and acts as an autocrine growth factor for small cell lung carcinoma
…, Y Jia, JA Keller, JK Blusztajn, GP Mark,ERSpindel- Cancer research, 2003 - AACR
It is well established that small cell lung carcinomas (SCLCs) express receptors for acetylcholine
(ACh) and that stimulation of these receptors by nicotine or other cholinergic agonists …
(ACh) and that stimulation of these receptors by nicotine or other cholinergic agonists …
Acetylcholine is an autocrine or paracrine hormone synthesized and secreted by airway bronchial epithelial cells
…,RD Blakely, J Lindstrom,ERSpindel- …, 2004 - academic.oup.com
The role of acetylcholine (ACh) as a key neurotransmitter in the central and peripheral nervous
system is well established. However, the role of ACh may be broader because ACh may …
system is well established. However, the role of ACh may be broader because ACh may …
Maternal nicotine exposure upregulates collagen gene expression in fetal monkey lung: Association with α 7 nicotinic acetylcholine receptors
…, BJ Proskocil, EL Martin,ERSpindel- American journal of …, 2002 - atsjournals.org
The recent identification of nicotinic acetylcholine receptors (nAChR) in pulmonary fibroblasts
suggests that in utero nicotine exposure may alter collagen expression by these cells in …
suggests that in utero nicotine exposure may alter collagen expression by these cells in …
Vitamin C supplementation for pregnant smoking women and pulmonary function in their newborn infants: a randomized clinical trial
Importance Maternal smoking during pregnancy adversely affects offspring lung development,
with lifelong decreases in pulmonary function and increased asthma risk. In a primate …
with lifelong decreases in pulmonary function and increased asthma risk. In a primate …
Pulmonary effects of maternal smoking on the fetus and child: effects on lung development, respiratory morbidities, and life long lung health
Maternal smoking during pregnancy is the largest preventable cause of abnormal in-utero
lung development. Despite well known risks, rates of smoking during pregnancy have only …
lung development. Despite well known risks, rates of smoking during pregnancy have only …
Prenatal nicotine exposure alters pulmonary function in newborn rhesus monkeys
…, JA Keller, NL Benowitz,ERSpindel- American journal of …, 2001 - atsjournals.org
Epidemiological studies have shown that offspring of women who smoke during pregnancy
have abnormal lung function and associated higher incidences of lower respiratory disorders…
have abnormal lung function and associated higher incidences of lower respiratory disorders…
Galanin is an estrogen-inducible, secretory product of the rat anterior pituitary
…, JI Koenig, ME Sunday,ERSpindel… - Proceedings of the …, 1988 - National Acad Sciences
Galanin is a peptide widely distributed throughout vertebrate central and peripheral nervous
systems. Although its precise physiologic role is unknown, it can stimulate the pituitary …
systems. Although its precise physiologic role is unknown, it can stimulate the pituitary …
Cloning and characterization of cDNAs encoding human gastrin-releasing peptide
ERSpindel, WW Chin, J Price… - Proceedings of the …, 1984 - National Acad Sciences
We have prepared and cloned cDNAs derived from poly(A)+ RNA from a human pulmonary
carcinoid tumor rich in immunoreactivity to gastrin-releasing peptide, a peptide closely …
carcinoid tumor rich in immunoreactivity to gastrin-releasing peptide, a peptide closely …
[HTML][HTML]Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates that it has a unique pharmacology …
…, RR Ryan, TK Pradhan, RP Searles,ERSpindel… - Journal of Biological …, 1997 - ASBMB
An orphan receptor discovered in 1993 was called bombesin receptor subtype 3 (BRS-3)
because of 47–51% amino acid identity with bombesin (Bn) receptors. Its pharmacology is …
because of 47–51% amino acid identity with bombesin (Bn) receptors. Its pharmacology is …