[HTML][HTML]Worldwide effects of coronavirus disease pandemic on tuberculosis services, January–April 2020

…, PB Njungfiyini, DJPalmero… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
Coronavirus disease has disrupted tuberculosis services globally. Data from 33 centers in 16
countries on 5 continents showed that attendance at tuberculosis centers was lower during …

Effectiveness and safety of bedaquiline-containing regimens in the treatment of MDR-and XDR-TB: a multicentre study

…, S Oelofse, M Ortelli, DJPalmero——欧洲…,2017 -欧元呼吸道Soc
Large studies on bedaquiline used to treat multidrug-resistant (MDR-) and extensively drug-resistant
tuberculosis (XDR-TB) are lacking. This study aimed to evaluate the safety and …

Surveillance of adverse events in the treatment of drug-resistant tuberculosis: first global report

…, L Nicod, MN Marcos, DJPalmero… - European …, 2019 - Eur Respiratory Soc
The World Health Organization (WHO) recommends that countries implement pharmacovigilance
and collect information on active drug safety monitoring (aDSM) and management of …

[HTML][HTML]Surveillance of adverse events in the treatment of drug-resistant tuberculosis: A global feasibility study

…, MN Marcos, NM Noordin, DJPalmero… - International journal of …, 2019 - Elsevier
The World Health Organization launched a global initiative, known as aDSM (active TB drug
safety monitoring and management) to better describe the safety profile of new treatment …

Outcomes of patients with drug-resistant-tuberculosis treated with bedaquiline-containing regimens and undergoing adjunctive surgery

…, PG Montaner, J Mullerpattan, DJPalmero… - Journal of Infection, 2019 - Elsevier
Objectives No study evaluated the contribution of adjunctive surgery in bedaquiline-treated
patients. This study describes treatment outcomes and complications in a cohort of drug-…

IL17A augments autophagy inMycobacterium tuberculosis-infected monocytes from patients with active tuberculosis in association with the severity of the disease

…, NO Amiano,A Rolandelli, N Casco, DJPalmero… - Autophagy, 2017 - Taylor & Francis
During mycobacterial infection, macroautophagy/autophagy, a process modulated by
cytokines, is essential for mounting successful host responses. Autophagy collaborates with …

[HTML][HTML]PGE2 displays immunosuppressive effects during human active tuberculosis

…, NO Amiano,A Rolandelli, DJPalmero… - Scientific reports, 2021 - nature.com
Prostaglandin E2 (PGE2), an active lipid compound derived from arachidonic acid, regulates
different stages of the immune response of the host during several pathologies such as …

Th22 response induced byMycobacterium tuberculosisstrains is closely related to severity of pulmonary lesions and bacillary load in patients with multi-drug …

…, L Moracho, NS Morcillo, DJPalmero… - Clinical & …, 2021 - academic.oup.com
The role of interleukin-22 (IL-22) in the pathogenesis or tissue repair in human tuberculosis (TB)
remains to be established. Here, we aimed to explore the ex-vivo and in-vitro T helper …

[HTML][HTML]The non-synonymous rs763780 single-nucleotide polymorphism in IL17f gene is associated with susceptibility to tuberculosis and advanced disease severity …

…, FA Castello, N Casco, A Levi, DJPalmero在201年…,…-前沿9 - frontiersin.org
Th17 lymphocytes, that produce IL17A, IL17F and IL22, play a crucial role during the immune
response against Mycobacterium tuberculosis (Mtb) infection. Whereas the contribution of …

Bedaquiline (BQ)-containing regimen at the programmatic level for MDR-TB: preliminary results

…, J Mullerpattan, S Oelofse, M Ortelli, DJPalmero… - 2017 - Eur Respiratory Soc
Introduction: Well designed studies on BQ used programmatically to treat M/XDR tuberculosis
(TB) are lacking. The aim of this study is to evaluate effectiveness and safety of BQ in a …