Mitochondrial transfer via tunneling nanotubes is an important mechanism by which mesenchymal stem cells enhance macrophage phagocytosis in the in vitro and in …
MV Jackson, TJ Morrison, DFDoherty, DF McAuley… - Stem …, 2016 - academic.oup.com
Mesenchymal stromal cells (MSC) have been reported to improve bacterial clearance in
preclinical models of Acute Respiratory Distress Syndrome (ARDS) and sepsis. The mechanism …
preclinical models of Acute Respiratory Distress Syndrome (ARDS) and sepsis. The mechanism …
Airway inflammation and host responses in the era of CFTR modulators
K Keown, R Brown, DFDoherty, C Houston… - International journal of …, 2020 - mdpi.com
The arrival of cystic fibrosis transmembrane conductance regulator (CFTR) modulators as a
new class of treatment for cystic fibrosis (CF) in 2012 represented a pivotal advance in …
new class of treatment for cystic fibrosis (CF) in 2012 represented a pivotal advance in …
Protein phosphatase 2A reduces cigarette smoke–induced cathepsin S and loss of lung function
DFDoherty, S Nath, J Poon, RF Foronjy… - American journal of …, 2019 - atsjournals.org
Rationale: CTSS (cathepsin S) is a cysteine protease that is observed at higher concentrations
in BAL fluid and plasma of subjects with chronic obstructive pulmonary disease (COPD). …
in BAL fluid and plasma of subjects with chronic obstructive pulmonary disease (COPD). …
Targeting of cathepsin S reduces cystic fibrosis-like lung disease
DM Small, RR Brown, DFDoherty… - European …, 2019 - Eur Respiratory Soc
Cathepsin S (CatS) is upregulated in the lungs of patients with cystic fibrosis (CF). However,
its role in CF lung disease pathogenesis remains unclear. In this study, β-epithelial Na + …
its role in CF lung disease pathogenesis remains unclear. In this study, β-epithelial Na + …
Cathepsin S contributes to lung inflammation in acute respiratory distress syndrome
…, AA Abladey, DM Small, DFDoherty… - American Journal of …, 2022 - atsjournals.org
Rationale: Although the cysteine protease cathepsin S has been implicated in the pathogenesis
of several inflammatory lung diseases, its role has not been examined in the context of …
of several inflammatory lung diseases, its role has not been examined in the context of …
The role of whey acidic protein four-disulfide-core proteins in respiratory health and disease
DM Small, DFDoherty, CM Dougan,S Weldon… - Biological …, 2017 - degruyter.com
Members of the whey acidic protein (WAP) or WAP four-disulfide-core (WFDC) family of
proteins are a relatively under-explored family of low molecular weight proteins. The two most …
proteins are a relatively under-explored family of low molecular weight proteins. The two most …
[HTML][HTML]Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice
R Brown, DM Small, DFDoherty, L Holsinger… - Mediators of …, 2021 - hindawi.com
Background. Elevated levels of the cysteine protease cathepsin S (CatS) are associated with
chronic mucoobstructive lung diseases such as cystic fibrosis (CF) and chronic obstructive …
chronic mucoobstructive lung diseases such as cystic fibrosis (CF) and chronic obstructive …
[PDF][PDF]Research Article Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice
R Brown, DM Small, DFDoherty, L Holsinger, R Booth… - 2021 - pureadmin.qub.ac.uk
Background. Elevated levels of the cysteine protease cathepsin S (CatS) are associated with
chronic mucoobstructive lung diseases such as cystic fibrosis (CF) and chronic obstructive …
chronic mucoobstructive lung diseases such as cystic fibrosis (CF) and chronic obstructive …
JAK-STAT Pathway Regulation of Intestinal Permeability: Pathogenic Roles and Therapeutic Opportunities in Inflammatory Bowel Disease
H Lei,MS Crawford,DF McCole- Pharmaceuticals, 2021 - mdpi.com
The epithelial barrier forms the interface between luminal microbes and the host immune
system and is the first site of exposure to many of the environmental factors that trigger disease …
system and is the first site of exposure to many of the environmental factors that trigger disease …
Folk. A Portrait of English Traditional Music, Musicians and Customs
M Yates - 1977 - JSTOR
… 1, andDeclan
F. Townsend replies to Breandan Breathnach's "Tus an phoirt in Eirinn". The
bibliography of Irish Folk Music is continued, and book and record reviews cover some of the …
bibliography of Irish Folk Music is continued, and book and record reviews cover some of the …