Objective We report on the effect of hemoadsorption therapy to reduce cytokines in septic
patients with respiratory failure. Methods This was a randomized, controlled, open-label, …

Purpose Guidelines recommend administering antibiotics within 1 h of sepsis recognition
but this recommendation remains untested by randomized trials. This trial was set up to …

Importance Survivors of sepsis face long-term sequelae that diminish health-related quality
of life and result in increased care needs in the primary care setting, such as medication, …

The term idiopathic pulmonary arterial hypertension (IPAH) is used to categorize patients with
pre-capillary pulmonary hypertension of unknown origin. There is considerable variability …

Background There have not yet been any prospective registry studies in Germany with active
investigation of the long-term survival of patients with sepsis. Methods The Jena Sepsis …

A decrease of small nerve fibers in skin biopsies during the course of critical illness has been
demonstrated recently. However, the diagnostic use of skin biopsies in sepsis and its time …

Background Current risk stratification tools in pulmonary arterial hypertension (PAH) are
limited in their discriminatory abilities, partly due to the assumption that prognostic clinical …

Background Risk stratification plays an essential role in the management of patients with
pulmonary arterial hypertension (PAH). The current European guidelines propose a 3-strata …

In patients with pulmonary hypertension associated with interstitial lung disease, pulmonary
vascular resistance provides stronger prognostic information than mean pulmonary arterial …

Purpose Infections and subsequent septicemia are major complications in neutropenic
patients with hematological malignancies. Here, we identify biomarker candidates for the early …