ContextThe结果帕特ients receiving mechanical ventilation for particular indications
has been studied, but the outcome in a large number of unselected, heterogeneous patients …

Background Weaning patients from mechanical ventilation is an important problem in intensive
care units. Weaning is usually conducted in an empirical manner, and a standardized …

Background Diffuse alveolar damage is the histological hallmark of acute respiratory distress
syndrome (ARDS). However, the chronology of histological lesions is not well established. …

Purpose Our objective was to revise the definition of acute respiratory distress syndrome (ARDS)
using a conceptual model incorporating reliability and validity, and a novel iterative …

Background The need for reintubation after extubation and discontinuation of mechanical
ventilation is not uncommon and is associated with increased mortality. Noninvasive positive-…

Importance Limited information exists about the epidemiology, recognition, management,
and outcomes of patients with the acute respiratory distress syndrome (ARDS). Objectives To …

A 2-h T-tube trial of spontaneous breathing was used in selecting patients ready for
extubation and discontinuation of mechanical ventilation. However, some doubt remains as to …

Rationale: Recent literature in mechanical ventilation includes strong evidence from
randomized trials. Little information is available regarding the influence of these trials on usual …

Rationale: Baseline characteristics and management have changed over time in patients
requiring mechanical ventilation; however, the impact of these changes on patient outcomes is …

Little information exists regarding the proportion of patients treated with mechanical ventilation
in intensive care units (ICUs), their underlying disease states, the modes of ventilation …