Chronic obstructive pulmonary disease (COPD) is one of the most common causes of death
worldwide. We report in an emphysema model of mice chronically exposed to tobacco …

Rationale: Chronic obstructive pulmonary disease (COPD) is a major cause of death worldwide.
No therapy stopping progress of the disease is available. Objectives: To investigate the …

Long-term cigarette smoking induces inflammatory processes in the pulmonary system that
are suggested to “spill over” into systemic inflammation. Regular exercise has been shown to …

Rationale Chronic obstructive pulmonary disease (COPD) is a widespread disease, with no
curative therapies available. Recent findings suggest a key role of NO and sGC-cGMP …

Chronic obstructive pulmonary disease (COPD), which comprises the phenotypes of chronic
bronchitis and emphysema, is often associated with pulmonary hypertension (PH). However…

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and
死亡率网络dwide. COPD is caused by chronic exposure to cigarette smoke and/or other …

Nitric oxide (NO) is an important regulator of Na + reabsorption by pulmonary epithelial cells
and therefore of alveolar fluid clearance. The mechanisms by which NO affects epithelial …

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and death
worldwide. Peroxynitrite, formed from nitric oxide, which is derived from inducible nitric oxide …

Background— Pulmonary hypertension (PH) is a life-threatening disease characterized by
vascular remodeling and increased pulmonary vascular resistance. Chronic alveolar hypoxia …

Background and Purpose Chronic obstructive pulmonary disease, encompassing chronic
airway obstruction and lung emphysema, is a major worldwide health problem and a severe …