von Willebrand factor in cardiovascular disease: focus on acute coronary syndromes
AOSpiel, JC Gilbert,B Jilma- Circulation, 2008 - Am Heart Assoc
von Willebrand factor (VWF) plays a pivotal role in platelet adhesion and aggregation at sites
高剪切rates (eg, in coronary arteries that have stenotic or ruptured atherosclerotic …
高剪切rates (eg, in coronary arteries that have stenotic or ruptured atherosclerotic …
Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrel
JM Siller-Matula, AOSpiel, IM Lang, G Kreiner… - American heart …, 2009 - Elsevier
Background Clopidogrel is activated by CYP2C19, which also metabolizes proton pump
inhibitors (PPI). As proton pump inhibitors are metabolized to varying degrees by CYP2C19, we …
inhibitors (PPI). As proton pump inhibitors are metabolized to varying degrees by CYP2C19, we …
Point-of-care ultrasonography in patients with acute dyspnea: an evidence report for a clinical practice guideline by the American College of Physicians
…, A Kaminski-Hartenthaler, AOSpiel- Annals of Internal …, 2021 - acpjournals.org
Background: Dyspnea is a common and often debilitating symptom with a complex diagnostic
work-up. Purpose: To evaluate the benefits, harms, and diagnostic test accuracy of point-of…
work-up. Purpose: To evaluate the benefits, harms, and diagnostic test accuracy of point-of…
In vivo profile of the human leukocyte microRNA response to endotoxemia
WM Schmidt, AOSpiel,B Jilma, M Wolzt… - … and biophysical research …, 2009 - Elsevier
To gain insight into microRNAs (miRNAs) involved in the regulation of the human innate
immune response, we screened for differentially expressed miRNAs in circulating leukocytes in …
immune response, we screened for differentially expressed miRNAs in circulating leukocytes in …
The aptamer ARC1779 is a potent and specific inhibitor of von willebrand factor mediatedex vivoplatelet function in acute myocardial infarction
AOSpiel,FB Mayr, N Ladani, PG Wagner, RG Schaub… - Platelets, 2009 - Taylor & Francis
ARC1779 is an aptamer, which blocks binding of the von Willebrand Factor (VWF) A1
domain to platelet GPIb receptors. VWF is increased in the elderly an in the setting of acute …
domain to platelet GPIb receptors. VWF is increased in the elderly an in the setting of acute …
Increased platelet aggregation and in vivo platelet activation after granulocyte colony-stimulating factor administration
AOSpiel, J Bartko, M Schwameis… - Thrombosis and …, 2011 - thieme-connect.com
Granulocyte colony-stimulating factor (G-CSF) stimulates the bone marrow to produce
granulocytes and stem cells and is widely used to accelerate neutrophil recovery after …
granulocytes and stem cells and is widely used to accelerate neutrophil recovery after …
Vernakalant is superior to ibutilide for achieving sinus rhythm in patients with recent-onset atrial fibrillation: a randomized controlled trial at the emergency department
…, C Weiser, AN Laggner, H Domanovits, AOSpiel- EP …, 2017 - academic.oup.com
Aims Ibutilide is a rapid-acting antiarrhythmic drug with worldwide use for conversion of
recent-onset atrial fibrillation. Vernakalant, approved in the EU in 2010, is likewise used …
recent-onset atrial fibrillation. Vernakalant, approved in the EU in 2010, is likewise used …
Hemostasis in cardiac arrest patients treated with mild hypothermia initiated by cold fluids
AOSpiel, A Kliegel, A Janata, T Uray,FB Mayr… - Resuscitation, 2009 - Elsevier
Aim of the study Application of mild hypothermia (32–33 C) has been shown to improve
neurological outcome in patients with cardiac arrest. However, hypothermia affects hemostasis, …
neurological outcome in patients with cardiac arrest. However, hypothermia affects hemostasis, …
Mortality in patients resuscitated from out-of-hospital cardiac arrest based on automated blood cell count and neutrophil lymphocyte ratio at admission
…, F Sterz, H Herkner, IM Lang, I Schwarzinger, AOSpiel- Resuscitation, 2017 - Elsevier
Introduction The neutrophil lymphocyte ratio(NLR) is a marker of systemic inflammation. We
hypothesized that admission NLR is related to mortality and that epinephrine application …
hypothesized that admission NLR is related to mortality and that epinephrine application …
Duffy antigen modifies the chemokine response in human endotoxemia
FB Mayr, AOSpiel, JM Leitner, C Firbas… - Critical care …, 2008 - journals.lww.com
Objective: The Duffy receptor is a promiscuous receptor for chemokines and selectively
binds CXC and CC chemokines with high affinity. Preclinical data show that presence of the …
binds CXC and CC chemokines with high affinity. Preclinical data show that presence of the …