User profiles forAdam Nelson

Adam Nelson

-Verified email at leeds.ac.uk -引用的5272

AdamJNelson

-Verified email at adelaide.edu.au -引用的3181

AdamGNelson

-Verified email at umich.edu -引用的580

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

…, PE Carlson,GE Hatton, AMNelson… - Nature …, 2014 - nature.com
Antibiotics can have significant and long-lasting effects on the gastrointestinal tract microbiota,
reducing colonization resistance against pathogens including Clostridium difficile. Here …

Pericardial fat is associated with atrial fibrillation severity and ablation outcome

CX Wong,HS Abed, P Molaee,AJNelson… - Journal of the American …, 2011 - jacc.org
Objectives : The aim of this study was to characterize the relationship between pericardial fat
and atrial fibrillation (AF). Background : Obesity is an important risk factor for AF. Pericardial …

OpenMC: A state-of-the-art Monte Carlo code for research and development

PK Romano, NE Horelik, BR Herman,AGNelson… - Annals of Nuclear …, 2015 - Elsevier
This paper gives an overview of OpenMC, an open source Monte Carlo particle transport
code recently developed at the Massachusetts Institute of Technology. OpenMC uses …

Obesity results in progressive atrial structural and electrical remodeling: implications for atrial fibrillation

…,R Mahajan, P Kuklik, Y Zhang, AG Brooks,AJNelson… - Heart rhythm, 2013 - Elsevier
Background Obesity is associated with atrial fibrillation (AF); however, the mechanisms by
which it induces AF are unknown. Objective To examine the effect of progressive weight gain …

[HTML][HTML]Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries

C Cordier,D Morton, S Murrison,ANelson… - Natural product …, 2008 - pubs.rsc.org
Covering: up to the end of August 2007 The purpose of diversity-oriented synthesis is to
drive the discovery of small molecules with previously unknown biological functions. Natural …

Synthesis of natural‐product‐like molecules with over eighty distinct scaffolds

…, S Leach, C Cordier,S Warriner,ANelson- Angewandte …, 2009 - Wiley Online Library
A key challenge in chemical biology is the design and synthesis of compound libraries
生成与生物相关的切大片mical space.[1–3] Libraries with high molecular …

Hypertension and atrial fibrillation: evidence of progressive atrial remodeling with electrostructural correlate in a conscious chronically instrumented ovine model

…, A Rajendram, DR Kelly, Y Zhang, P Kuklik,AJNelson… - Heart rhythm, 2010 - Elsevier
Background Hypertension accounts for more atrial fibrillation (AF) than any other predisposing
factor. Objective The purpose of this study was to characterize the time course, extent, …

Evolutionary Genetics of a New PathogenicEscherichiaSpecies:Escherichiaalbertiiand RelatedShigellaboydiiStrains

KE Hyma, DW Lacher, AMNelson… - Journal of …, 2005 - Am Soc Microbiol
A bacterium originally described as Hafniaalvei induces diarrhea in rabbits and causes
epithelial damage similar to the attachment and effacement associated with enteropathogenic …

Complement blockade for TA-TMA: lessons learned from a large pediatric cohort treated with eculizumab

…, A Teusink-Cross,KC Myers, G Wallace, ANelson… - Blood, 2020 - ashpublications.org
Overactivated complement is a high-risk feature in hematopoietic stem cell transplant (HSCT)
recipients with transplant-associated thrombotic microangiopathy (TA-TMA), and untreated …

Recent advances and applications of iridium-catalysed asymmetric allylic substitution

P Tosatti,ANelson,SP Marsden- Organic & Biomolecular Chemistry, 2012 - pubs.rsc.org
… andAdam Nelson. During this time he applied metal-catalysed asymmetric allylic substitutions
to the array synthesis of lead-like molecules as part of a collaborative project between the …