Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection
…, PE Carlson,GE Hatton, AMNelson… - Nature …, 2014 - nature.com
Antibiotics can have significant and long-lasting effects on the gastrointestinal tract microbiota,
reducing colonization resistance against pathogens including Clostridium difficile. Here …
reducing colonization resistance against pathogens including Clostridium difficile. Here …
Pericardial fat is associated with atrial fibrillation severity and ablation outcome
Objectives : The aim of this study was to characterize the relationship between pericardial fat
and atrial fibrillation (AF). Background : Obesity is an important risk factor for AF. Pericardial …
and atrial fibrillation (AF). Background : Obesity is an important risk factor for AF. Pericardial …
OpenMC: A state-of-the-art Monte Carlo code for research and development
This paper gives an overview of OpenMC, an open source Monte Carlo particle transport
code recently developed at the Massachusetts Institute of Technology. OpenMC uses …
code recently developed at the Massachusetts Institute of Technology. OpenMC uses …
Obesity results in progressive atrial structural and electrical remodeling: implications for atrial fibrillation
Background Obesity is associated with atrial fibrillation (AF); however, the mechanisms by
which it induces AF are unknown. Objective To examine the effect of progressive weight gain …
which it induces AF are unknown. Objective To examine the effect of progressive weight gain …
[HTML][HTML]Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries
Covering: up to the end of August 2007 The purpose of diversity-oriented synthesis is to
drive the discovery of small molecules with previously unknown biological functions. Natural …
drive the discovery of small molecules with previously unknown biological functions. Natural …
Synthesis of natural‐product‐like molecules with over eighty distinct scaffolds
…, S Leach, C Cordier,S Warriner,ANelson- Angewandte …, 2009 - Wiley Online Library
A key challenge in chemical biology is the design and synthesis of compound libraries
生成与生物相关的切大片mical space.[1–3] Libraries with high molecular …
生成与生物相关的切大片mical space.[1–3] Libraries with high molecular …
Hypertension and atrial fibrillation: evidence of progressive atrial remodeling with electrostructural correlate in a conscious chronically instrumented ovine model
…, A Rajendram, DR Kelly, Y Zhang, P Kuklik,AJNelson… - Heart rhythm, 2010 - Elsevier
Background Hypertension accounts for more atrial fibrillation (AF) than any other predisposing
factor. Objective The purpose of this study was to characterize the time course, extent, …
factor. Objective The purpose of this study was to characterize the time course, extent, …
Evolutionary Genetics of a New PathogenicEscherichiaSpecies:Escherichiaalbertiiand RelatedShigellaboydiiStrains
KE Hyma, DW Lacher, AMNelson… - Journal of …, 2005 - Am Soc Microbiol
A bacterium originally described as Hafniaalvei induces diarrhea in rabbits and causes
epithelial damage similar to the attachment and effacement associated with enteropathogenic …
epithelial damage similar to the attachment and effacement associated with enteropathogenic …
Complement blockade for TA-TMA: lessons learned from a large pediatric cohort treated with eculizumab
…, A Teusink-Cross,KC Myers, G Wallace, ANelson… - Blood, 2020 - ashpublications.org
Overactivated complement is a high-risk feature in hematopoietic stem cell transplant (HSCT)
recipients with transplant-associated thrombotic microangiopathy (TA-TMA), and untreated …
recipients with transplant-associated thrombotic microangiopathy (TA-TMA), and untreated …
Recent advances and applications of iridium-catalysed asymmetric allylic substitution
P Tosatti,ANelson,SP Marsden- Organic & Biomolecular Chemistry, 2012 - pubs.rsc.org
… andAdam
Nelson. During this time he applied metal-catalysed asymmetric allylic substitutions
to the array synthesis of lead-like molecules as part of a collaborative project between the …
to the array synthesis of lead-like molecules as part of a collaborative project between the …