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。 2019年11月28日； 54（5）：1900861。
doi: 10.1183/13993003.00861-2019. 印刷2019年11月。

Latent tuberculosis screening and treatment among asylum seekers: a mixed-methods study

Ineke Spruijt12，，，， Dawit Tesfay Haile2，，，， Jeanine Suurmond2，，，， Susan van den Hof34，，，， Marga Koenders5，，，， Peter Kouw6，，，， Natascha van Noort7，，，， 索菲·托马尼亚人8，，，， Frank Cobelens9，，，， Simone Goosen10，，，， Connie Erkens3
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Latent tuberculosis screening and treatment among asylum seekers: a mixed-methods study

Ineke Spruijt等。 Eur Respir J。 。
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Abstract

Introduction:Evidence on conditions for implementation of latent tuberculosis infection (LTBI) screening and treatment among asylum seekers is needed to inform tuberculosis (TB) control policies. We used mixed-methods to evaluate the implementation of an LTBI screening and treatment programme among asylum seekers in the Netherlands.

Methods:We offered voluntary LTBI screening to asylum seekers aged ≥12 years living in asylum seeker centres from countries with a TB incidence >200 per 10 000 population. We calculated LTBI screening and treatment cascade coverage, and assessed associated factors with Poisson regression using robust variance estimators. We interviewed TB care staff (seven group interviews) and Eritrean clients (21 group and 21 individual interviews) to identify programme enhancers and barriers.

Results:我们为LTBI筛选了719个客户端（1136个客户端的63％）。LTBI在178名（25％）客户中被诊断出；149（84％）开始了LTBI治疗，其中129（87％）完成了治疗。面对面的结核病和LTBI教育，专业口译员的使用以及与合作伙伴组织的合作是LTBI筛选吸收的增强剂。TB护士受需求驱动的LTBI治疗支持增强了治疗的完成。复杂的LTBI筛查和治疗的因素不得不前往公共卫生服务，语言障碍，并在治疗期间从寻求庇护者中心转移到社区。

Conclusion:LTBI screening and treatment of asylum seekers is feasible and effective when high quality of care is provided, including culture-sensitive TB education throughout the care cascade. Additionally, collaboration with partner organisations, such as agencies responsible for reception and support of asylum seekers, should be in place.

Conflict of interest statement

利益冲突：I。Spruijt在研究过程中报告了KNCV结核病基金会的赠款和其他赠款。利益冲突：D。TesfayHaile没有什么可披露的。利益冲突：J。Suurmond没有什么可披露的。利益冲突：S。van den Hof没有什么可披露的。利益冲突：M。Koenders没有什么可披露的。利益冲突：P。Kouw没有什么可披露的。利益冲突：N。VanNoort无需透露。利益冲突：S。Toumanian无话可说。利益冲突：F。Cobelens无话可说。利益冲突：S。Goosen没有什么可披露的。 Conflict of interest: C. Erkens has nothing to disclose.

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