兴趣冲突：K. Geale报道了Novartis的研究项目资助当前的工作;在研究期间和提交的工作之外，在研究期间，咨询研究中的顾问费用。利益冲突：H. Darabi报告了Novartis的研究项目资金，以获取当前的工作;在研究期间和提交的工作之外，在研究期间，咨询研究中的顾问费用。兴趣冲突：M. Lindh报告从诺华州的研究项目资助当前的工作;在研究期间和提交的工作之外，在研究期间，咨询研究中的顾问费用。利益冲突：H. Fues Wahl报告了Novartis的研究项目资金，以获取当前的工作;在研究期间和提交的工作之外，在研究期间，咨询研究中的顾问费用。利益冲突：O.Tröm报告了Novartis的研究项目资金，用于目前的工作;在研究期间和提交的工作之外，在研究期间，咨询研究中的顾问费用。 Conflict of interest: H. Cao is an employee of Novartis Pharmaceutical Company. Conflict of interest: L.A. Alvares is an employee of Novartis. Conflict of interest: R. Dodge has nothing to disclose. Conflict of interest: E. Loefroth is an employee of Novartis. Conflict of interest: A. Altraja reports personal fees and travel and educational support from AstraZeneca, Berlin-Chemie Menarini, Boehringer Ingelheim, CSL Behring, Roche, Teva and Sanofi, grants, personal fees and travel and educational support from Chiesi (Norameda) and GlaxoSmithKline, personal fees and travel support from MSD, grants and personal fees from Bayer, travel and educational support from Actelion (Johnson and Johnson), personal fees from Shire Pharmaceuticals, outside the submitted work. Conflict of interest: V. Backer has nothing to disclose. Conflict of interest: H. Backman reports personal fees for lectures from AstraZeneca, outside the submitted work. Conflict of interest: L. Bjermer reports personal fees from AstraZeneca, Boehringer, Chiesi, GSK, Novartis, Teva and ALK, outside the submitted work. Conflict of interest: A. Bossios reports personal fees for advisory board work and/or lectures from AZ, Teva, GSK and Novartis, outside the submitted work. Conflict of interest: B. Bøgvald Aarli reports personal fees for lectures from Boehringer Ingelheim, Novartis, AstraZeneca, Chiesi and Alere, personal fees for consultancy from GlaxoSmithKline, and has stock in from KBB Medic AS, outside the submitted work. Conflict of interest: B. Dahlén reports personal fees for lectures and advisory board work from AstraZeneca, GSK, Teva, Sanofi and Novartis, outside the submitted work. Conflict of interest: O. Hilberg has nothing to disclose. Conflict of interest: C. Jansson has nothing to disclose. Conflict of interest: H. Kankaanranta reports grants, personal fees for lectures and consultancy, and non-financial support to attend meetings from AstraZeneca, personal fees for lectures and consultancy from Chiesi Pharma AB, Novartis and GlaxoSmithKline, personal fees for lectures and consultancy, and non-financial support to attend meetings from Boehringer Ingelheim and Orion Pharma, personal fees for lectures from Mundipharma, personal fees for consultancy from Sanofi Genzyme, outside the submitted work. Conflict of interest: J. Karjalainen reports personal fees from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Mundipharma, Novartis, Orion Pharma and Teva, outside the submitted work. Conflict of interest: P. Kauppi reports personal fees for lectures from GSK, Teva and Novartis, personal fees for manuscript preparation from Fimea, personal fees for consultancy from Sanofi, outside the submitted work. Conflict of interest: M. Kilpeläinen has nothing to disclose. Conflict of interest: S. Lehmann reports data analysis and manuscript preparation support from Novartis, during the conduct of the study; personal fees for lectures from AstraZeneca, personal fees for manuscript preparation from Boehringer Ingelheim, outside the submitted work. Conflict of interest: L. Lehtimäki reports personal fees from AstraZeneca, Chiesi, GSK, Boehringer Ingelheim, MSD, Novartis, pi tlsb -.005wOrionPharma, ALK, Teva and Sanofi, outside the submitted work. Conflict of interest: B. Lundbäck reports grants from AstraZeneca, personal fees for lectures and advisory board work from AstraZeneca, Novartis, GSK and Sanofi, outside the submitted work. Conflict of interest: T. Sandström has nothing to disclose. Conflict of interest: C. Suppli. Ulrik has nothing to disclose. Conflict of interest: A. Sverrild has nothing to disclose. Conflict of interest: A. Viinanen has nothing to disclose. Conflict of interest: A. von Bülow has nothing to disclose. Conflict of interest: V. Yasinska has nothing to disclose. Conflict of interest: C. Porsbjerg reports grants and personal fees from AstraZeneca, GSK, Novartis, Sanofi and Teva, outside the submitted work.