Prevalence of gastroesophageal reflux symptoms in asthma
- PMID：8620699.
- DOI:10.1378 / chess.109.2.316
Prevalence of gastroesophageal reflux symptoms in asthma
抽象的
Study objective:确定症状胃食管反流（GER），回流相关呼吸系统症状（RARS）和回流相关β-激动剂吸入器在哮喘中使用的患病率。
Design:Questionnaire-based, cross-sectional analytic survey.
环境：Outpatient asthma and clinical research clinics attached to the University of Calgary tertiary care centre and two family practices.
Patients:Asthma group consisted of 109 patients referred to an outpatient asthma clinic. First control group consisted of 68 patients visiting their family physicians. Second control group consisted of 67 patients with thyroid disease, hypercholesterolemia, or diabetes participating in drug trials.
Results:哮喘学，77％，55％和24％，分别经历了胃灼热，反流和吞咽困难。对照组症状较少普遍。至少一种抗亚替司司药物需要37％的哮喘（P <0.001，VS对照）。没有一种哮喘药物与症状药物的可能性增加有关。在完成调查问卷前的一周内，41％的哮喘学指出rars，包括咳嗽，呼吸困难和喘息，28％在体验GER症状时使用吸入器。吸入器使用与胃灼热的严重程度相关（r = 0.28，p <0.05）和反流性（r = 0.40，p <0.05）
结论：调查问卷表现出GER症状，RAR和回流相关吸入器在哮喘中使用的更大普遍性。这种过度吸入器使用可以解释GER如何间接导致哮喘恶化。
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