胸内的公关效果essure on left ventricular performance
- PMID:460363
- DOI:10.1056/NEJM197908303010901
胸内的公关效果essure on left ventricular performance
Abstract
Left ventricular dysfunction is common in respiratory-distress syndrome, asthma and obstructive lung disease. To understand the contribution of intrathoracic pressure to this problem, we studied the effects of Valsalva and Müller maneuvers on left ventricular function in eight patients. Implantation of intramyocardial markers permitted beat-by-beat measurement of the velocity of fiber shortening (VCF) and left ventricular volume. During the Müller maneuver, VCF and ejection fraction decreased despite an increase in left ventricular volume and a decline in arterial pressure. In addition, when arterial pressure was corrected for changes in intrapleural pressure during either maneuver it correlated better with left ventricular end-systolic volumes than did uncorrected arterial pressures. These findings suggest that negative intrathoracic pressure affects left ventricular function by increasing left ventricular transmural pressures and thus afterload. We conclude that large intrathoracic-pressure changes, such as those that occur in acute pulmonary disease, can influence cardiac performance.
Similar articles
-
Effect of early postoperative volume loading on left ventricular systolic function (including left ventricular ejection fraction determined by myocardial marker) after myocardial revascularization.Circulation. 1985 Sep;72(3 Pt 2):II207-15. Circulation. 1985. PMID:3896554
-
The Valsalva maneuver: mechanisms and clinical implications.Heart Lung. 1984 Sep;13(5):507-18. Heart Lung. 1984. PMID:6565684
-
[Left ventricular function in chronic obstructive lung disease (author's transl)].Bull Eur Physiopathol Respir. 1979 Sep-Oct;15(5):755-72. Bull Eur Physiopathol Respir. 1979. PMID:159743 French.
-
[Echocardiographic determination of left ventricular function during isometric muscle exertion and the Valsalva maneuver].Acta Med Austriaca. 1978;5(4-5):124-5. Acta Med Austriaca. 1978. PMID:756118 German.
-
Theophylline improves global cardiac function and reduces dyspnea in chronic obstructive lung disease.J Allergy Clin Immunol. 1986 Oct;78(4 Pt 2):793-9. doi: 10.1016/0091-6749(86)90063-1. J Allergy Clin Immunol. 1986. PMID:3534060 Review.
Cited by115articles
-
Risk factors associated with the severity of obstructive sleep apnea syndrome among adults.Sci Rep. 2020 Aug 11;10(1):13508. doi: 10.1038/s41598-020-70286-6. Sci Rep. 2020. PMID:32782271 Free PMC article.
-
Brain natriuretic peptide to predict successful liberation from mechanical ventilation in critically ill patients: a systematic review and meta-analysis.Crit Care. 2020 May 11;24(1):213. doi: 10.1186/s13054-020-2823-9. Crit Care. 2020. PMID:32393393 Free PMC article.
-
Sleep Disordered Breathing in Hypertrophic Cardiomyopathy-Current State and Future Directions.J Clin Med. 2020 Mar 25;9(4):901. doi: 10.3390/jcm9040901. J Clin Med. 2020. PMID:32218147 Free PMC article. Review.
-
Pulmonary edema following diuretic therapy: A case report.Medicine (Baltimore). 2020 Feb;99(8):e19180. doi: 10.1097/MD.0000000000019180. Medicine (Baltimore). 2020. PMID:32080100 Free PMC article.
-
CArtesian sampling with Variable density and Adjustable temporal resolution (CAVA).Magn Reson Med. 2020 Jun;83(6):2015-2025. doi: 10.1002/mrm.28059. Epub 2019 Nov 12. Magn Reson Med. 2020. PMID:31721303
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical