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Hypertension

肺动脉高压挑战的定义?

The current definition of pulmonary hypertension (PH) is based on resting mean pulmonary arterial pressure (mPAP) ≥25 mmHg; however, analysis of long-term follow-up data now reveals increased mortality even with mPAP ≥19 mmHg. Do we need to modify the definition of PH, and what are the implications for clinical practice?

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参考

  1. Galie,N。et al。2015 ESC/ERS guidelines for the diagnosis and treatment of pulmonary hypertension: the Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).欧元。心J.37,67-119(2016)。

    文章Google Scholar

  2. Kovacs, G., Berghold, A., Scheidl, S. & Olschewski, H. Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review.欧元。Respir. J.34, 888–894 (2009).

    CAS文章Google Scholar

  3. Badesch,D .B。et al。Diagnosis and assessment of pulmonary arterial hypertension.J. Am. Coll. Cardiol.54(SUPPLS。),S55-S66(2009)。

    文章Google Scholar

  4. Maron,B. A.et al。Association of borderline pulmonary hypertension with mortality and hospitalization in a large patient cohort: insights from the VA-CART Program.Circulationhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.020207(2016)。

  5. D'Alonzo, G. E.et al。初级肺动脉高压患者的存活:国家前瞻性登记处的结果。Ann. Intern. Med.115,343-349(1991)。

    CASPubMedGoogle Scholar

  6. Robin, E. D. The kingdom of the near-dead. The shortened unnatural life history of primary pulmonary hypertension.Chest92,330-334(1987)。

    CAS文章Google Scholar

  7. Lewczuk, J.et al。医学治疗慢性肺栓塞患者的预后因素。Chest119, 818–823 (2001).

    CAS文章Google Scholar

  8. Riedel, M., Stanek, V., Widimsky, J. & Prerovsky, I. Longterm follow-up of patients with pulmonary thromboembolism: late prognosis and evolution of hemodynamic and respiratory data.Chest81,151-158(1982年)。

    CAS文章Google Scholar

  9. Herve, P.et al。运动肺动脉高压诊断标准。欧元。Respir. J.46,728-737(2015)。

    文章Google Scholar

  10. Naeije,R.,Vonk Noordegraaf,A.&Kovacs,G.运动诱导的肺动脉高压:终于!欧元。Respir. J.46,583-586(2015)。

    CAS文章Google Scholar

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对应于Adam Torbicki

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Competing interests

A.T. declares that he has received honoraria for lectures and consultancy as well as investigator's honoraria from Actelion, AOP Orphan Pharmaceuticals, Bayer, MSD, and United Therapeutics.

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Torbicki,A.肺动脉高压挑战的定义?Nat Rev Cardiol13,250-251(2016). https://doi.org/10.1038/nrcardio.2016.44

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