The current definition of pulmonary hypertension (PH) is based on resting mean pulmonary arterial pressure (mPAP) ≥25 mmHg; however, analysis of long-term follow-up data now reveals increased mortality even with mPAP ≥19 mmHg. Do we need to modify the definition of PH, and what are the implications for clinical practice?
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A.T. declares that he has received honoraria for lectures and consultancy as well as investigator's honoraria from Actelion, AOP Orphan Pharmaceuticals, Bayer, MSD, and United Therapeutics.
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Torbicki,A.肺动脉高压挑战的定义?Nat Rev Cardiol13,250-251(2016). https://doi.org/10.1038/nrcardio.2016.44
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DOI:https://doi.org/10.1038/nrcardio.2016.44