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右心肺动脉相互作用

Abstract

The application of pulsatile models to hemodynamic data has made possible a more complete understanding of the relationship of pulmonary pressure and flow. To review the genesis of these concepts, the unique characteristics of the pulmonary artery and right ventricle are outlined as a basis for understanding why differences in their pulsatile properties from the systemic circuit must exist. The pulmonary impedance spectrum is introduced and the concept of optimal right ventricular-pulmonary artery coupling is explored based on a review of extensive experimental data. Finally, available studies of normal pulmonary impedance in man and abnormal impedance in human disease states are reviewed, with emphasis on disturbances in optimal ventricular-vascular coupling. The important implications of these concepts for understanding and treatment of cardiovascular disease are developed.

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参考

  1. Altschuler,J.A。;W.K. Laskey;H.C. Herrmann;Kussmaul W.G.心动过速改变二尖瓣狭窄中的右心血管耦合。循环78:ii-125;1988。

    谷歌学术

  2. Arani,D.T。;Carleton,R.A。心动过速在二尖瓣狭窄中的有害作用。循环86:511–516;1967年。

    谷歌学术

  3. Bergel,D.H。;Milnor, W.R. Pulmonary vascular impedance in the dog. Circ. Res. 16:401–415; 1965.

    CASPubMed谷歌学术

  4. Caro,C.G。;麦当劳D.A.脉冲压力和肺血管床中流动的关系。J. Physiol。157:426–453;1961年。

    CASPubMed谷歌学术

  5. Elkins, R.C.; Milnor, W.R. Pulmonary vascular response to exercise in the dog. Circ. Res. 29:591–599; 1971.

    CASPubMed谷歌学术

  6. Engelberg,J。;Dubois,A.B。孤立兔肺中肺循环的力学。是。J. Physiol。196:401–414;1959年。

    CASPubMed谷歌学术

  7. Gurtner,H.P。;Walser,P。;Fassler,B。静止和运动过程中肺血液动力学的正常值。prog。解答res。9:295–315;1975年。

    谷歌学术

  8. Haneda, T.; Nakajima, T.; Shirato, K.; Onodera, S.; Takishima, T. Effects of oxygen breathing on pulmonary vascular input impedance in patients with pulmonary hypertension. Chest. 83:520–526; 1983.

    CASPubMed谷歌学术

  9. 霍普金斯,R.A。;Hammon,J.W。;麦克海尔(P.A.);史密斯,P.K。;Anderson,R.W。对清醒狗中肺循环对急性和慢性肺静脉高血压的脉动血液动力学反应的分析。循环。res。47:902–910;1980年。

    CASPubMed谷歌学术

  10. Janicki, J.S.; Weber, K.T.; Likoff, M.J.; Fishman, A.P. The pressure-flow response of the pulmonary circulation in patients with heart failure and pulmonary vascular disease. Circulation 72:1270–1278; 1985.

    CASPubMed谷歌学术

  11. W.G. Kussmaul;Wieland, J.M.; Laskey, W.K. Pressure flow relations in the pulmonary artery during myocardial ischemia: Implications for right ventricular function in coronary artery disease. Cardiovasc. Res. 22:627–638; 1988.

    CASPubMed谷歌学术

  12. W.K. Laskey;W.G. Kussmaul;Martin,J.L。;Kleaveland,J.P。;Hirshfeld,J.W。;Shroff,S。心力衰竭患者血管液压负荷的特征。循环72:61–71;1985。

    CASPubMed谷歌学术

  13. W.K. Laskey;Kussmaul,W.G。心力衰竭中的动脉波反射。循环75:711–721;1987。

    CASPubMed谷歌学术

  14. Lucas, C.L.; Radke, N.F.; Wilcox, B.R.; Henry, G.W.; Keagy, B.A. Maturation of pulmonary input impedance spectrum in infants and children with ventricular septal defect. Am. J. Cardiol. 57:821–827; 1986.

    ArticleCASPubMed谷歌学术

  15. Mills, C.J.; Gabe, I.T.; Gault, J.H.; Mason, D.T.; Ross, J., Jr.; Braunwald, E.; Shillingford, J.P. Pressure-flow relationships and vascular impedance in man. Cardio. Res. 4:405–417; 1970.

    CAS谷歌学术

  16. W.R. Milnor;Bergel,D.H。;讨价还价,J.D。与肺血流相关的液压功率及其与心率的关系。循环。res。19:467–480;1966年。

    CASPubMed谷歌学术

  17. W.R. Milnor;Conti, C.R.; Lewis, K.B.; O'Rourke, M.F. Pulmonary artery pulse wave velocity and impedance in man. Circ. Res. 25:637–649; 1969.

    CASPubMed谷歌学术

  18. 米尔诺尔,得到心室尾动脉阻抗erload. Circ. Res. 36:565–570; 1975.

    CASPubMed谷歌学术

  19. 莫里森,d。;Sorensen,S。;Caldwell,J。;Wright,A.L。;Ritchie,J。;肯尼迪(J.W.);Hamilton,G。仰卧运动的正常右心室反应。胸部。6:686–691;1982。

    谷歌学术

  20. Murgo,J.P。;Altobelli, S.A.; Dorethy, J.F.; Logsdon, J.R.; McGranahan, G.M. Normal ventricular ejection dynamics in man during rest and exercise. Am. Heart Assoc. Monog. 46:92–101; 1975.

    谷歌学术

  21. Murgo,J.P。;Westerhof,n。;Giolma,J.P。;正常人中的Altobelli,S.A。主动脉输入阻抗:与压力波形的关系。循环62:105–115;1980年。

    CASPubMed谷歌学术

  22. Murgo,J.P。;Westerhof,n。;Giolma,J.P。;Altobelli, S.A. Effects of exercise on aortic input impedance and pressure wave forms in normal humans. Circ. Res. 48:334–343; 1981.

    CASPubMed谷歌学术

  23. Murgo,J.P。;Westerhof, N. Input impedance of the pulmonary arterial system in normal man. Circ. Res. 54:666–673; 1984.

    CASPubMed谷歌学术

  24. O'Rourke,M。动脉和心脏功能研究中的血管阻抗。生理学。启62:570–623;1982。

    PubMed谷歌学术

  25. 速度,J.B。麻醉犬中肺血管阻抗的交感神经控制。循环。res。29:555–568;1971年。

    CASPubMed谷歌学术

  26. Pace, J.B.; Cox, R.H.; Alvarez-Vara, F.; Karreman, G. Influence of sympathetic nerve stimulation on pulmonary hydraulic input power. Am. J. Physiol. 222:196–201; 1972.

    CASPubMed谷歌学术

  27. Pasipoularides,A。对有和没有流出阻塞的心室射血动力学的临床评估。J. Am。科尔。Cardiol。15:859–882;1990。

    CASPubMed谷歌学术

  28. 帕特尔(D.J.);Defreitas,F.M。;Fry,D.L。对狗的主动脉和肺动脉的液压输入阻抗。J. Appl。生理学。18:134–140;1963年。

    CASPubMed谷歌学术

  29. Piene, H. The influence of pulmonary blood flow rate on vascular input impedance and hydraulic power in the sympathetically and noradrenaline stimulated cat lung. Act. Physiol. Scand. 98:44–53; 1976.

    CAS谷歌学术

  30. 皮恩(H。)Sund,T。右心室的流量和功率输出面向负载,并具有可变的输入阻抗。是。J. Physiol。237:H125-H130;1979年。

    CASPubMed谷歌学术

  31. Piene,H。右心室及其动脉负荷之间的相互作用:定量溶液。是。J. Physiol。238:H932-H937;1980年。

    CASPubMed谷歌学术

  32. 皮恩(H。)Sund, T. Does normal pulmonary impedance constitute the optimum load for the right ventricle? Am. J. Physiol. 242:H154-H160; 1982.

    CASPubMed谷歌学术

  33. Piene,H。与肺动脉阻抗有关的右心室功能。在:Suga,K。;Baan,J。;Yellin,E。,编辑:正常和患病的心脏中的心脏力学和功能。纽约:Springer-Verlag;1989年:第211-224页。

    谷歌学术

  34. Pollack,G.H。;R.V. Reddy;Noordergraaf,A。人类肺动脉树中的输入阻抗,波浪行进和反射:使用电类似物进行研究。反式。生物。工程。BME 15:151–164;1968年。

    CAS谷歌学术

  35. Pouleur,H。;Lefevre,J。;范·艾尔(Van Eyll),c。Jaumin,P.M。;Charlier,A.A。肺输入阻抗在右心室性能中的重要性。有氧运动。res。12:617–629;1978年。

    CAS谷歌学术

  36. Reuben, S.R.; Kitchin, A.H.. Pulmonary artery input impedance in pulmonary hypertension. Prog. Resp. Res. 9:261–266; 1975.

    谷歌学术

  37. Reuben, S.R.; Swadling, J.P.; Gersh, B.J.; Lee, G. Impedance and transmission properties of the pulmonary arterial system. Cardiovasc. Res. 5:1–9; 1971.

    谷歌学术

  38. Stanek, V.; Widimsky, J.; Degre, S.; Denolin, H. The lesser circulation during exercise in healthy subjects. Prog. Resp. Res. 9:1–9; 1975.

    谷歌学术

  39. Vanden Bos,G.C。;Westerhof,n。;兰德尔,O.S。脉搏波反射:它可以解释全身和肺部压力和流动波之间的差异吗?循环。res。51:479–485;1982。

    PubMed谷歌学术

  40. Westerhof,n。;Sipkema,P。;Van den Bos,G.C。;Elzinga,C。动脉系统中的前后波。有氧运动。res。6:648–656;1972年。

    CAS谷歌学术

  41. 维纳(Wiener),f。;Morkin,E。;Skalak,r。Fishman,A.P。肺循环中的波传播。循环。res。19:834–850;1966年。

    CASPubMed谷歌学术

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Kussmaul, W.G., Noordergraaf, A. & Laskey, W.K. Right ventricular-pulmonary arterial interactions.Ann Biomed Eng20,63–80 (1992). https://doi.org/10.1007/BF02368506

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关键字

  • Pulmonary impedance
  • 右心室功能
  • Ventricular-vascular coupling