Cox regression analysis of factors associated with prolonged severe acute respiratory syndrome coronavirus 2 positivity
| Univariate analysis | Multivariate analysis | |||
| p-value | HR (95% CI) | p-value | HR (95% CI) | |
| Age | 0.335 | 1.013 (0.987–1.041) | 0.831 | 0.995 (0.954–1.03) |
| Sex (male=1, female=2) | 0.415 | 1.395 (0.627–3.102) | 0.077 | 2.531 (0.905–7.073) |
| Disease severity (severe=1, nonsevere=0) | 0.075 | 1.894 (0.939–3.824) | 0.025* | 3.260 (1.162–9.147) |
| Oxygen insufflation necessary (yes=1, no=0) | 0.573 | 1.321 (0.502–3.473) | 0.057 | 3.960 (0.961–16.319) |
| Hydroxychloroquine therapy (yes=1, no=0) | 0.082 | 0.490 (0.219–1.095) | 0.263 | 0.597 (0.242–1.474) |
| Lopinavir/ritonavir treatment (yes=1, no=0) | 0.796 | 1.149 (0.401–3.296) | 0.384 | 1.713 (0.509–5.765) |
| Immunosuppressive treatment (tocilizumab/prednisolone/others; yes=1, no=0) | 0.233 | 1.723 (0.704–4.215) | 0.110 | 2.748 (0.794–9.511) |
| 糖尿病(= 1,否= 0) | 0.953 | 0.975 (0.422–2.254) | 0.704 | 1.243 (0.404–3.825) |
| Arterial hypertension (yes=1, no=0) | 0.621 | 1.193 (0.593–2.401) | 0.572 | 0.765 (0.302–1.939) |
| Coronary artery disease (yes=1, no=0) | 0.787 | 1.141 (0.440–2.959) | 0.968 | 0.978 (0.326–2.930) |
| Charlson Comorbidity Index (0–7) | 0.425 | 1.082 (0.891–1.314) | 0.850 | 1.036 (0.719–1.493) |
HR: hazard ratio. *: p<0.05.