Daily adherence to maintenance therapy over months 4–6 by baseline asthma control test (ACT) total score and by age group, with the difference in arms 1–4versusarm 5
| Months 4–6 | Arm 1 (n=87) | Arm 2 (n=88) | Arm 3 (n=88) | Arm 4 (n=88) | Arm 5 (n=86) |
| Baseline ACT total score: ≤15 | |||||
| n# | 28 | 31 | 41 | 29 | 33 |
| Least squares mean±se% | 82.7±4.61 | 82.4±4.51 | 75.5±3.99 | 75.6±4.61 | 64.5±4.36 |
| CIS armversusarm 5 | |||||
| Difference % | 18.3 | 18.0 | 11.0 | 11.2 | |
| 95%可信区间% | 7.1–29.5 | 7.2–28.7 | 1.0–21.1 | 0.1–22.2 | |
| Baseline ACT total score: 16–19 | |||||
| n# | 55 | 53 | 43 | 53 | 52 |
| Least squares mean±se% | 80.7±3.66 | 74.8±3.45 | 81.7±3.90 | 78.5±3.70 | 72.7±3.76 |
| CIS armversusarm 5 | |||||
| Difference % | 8.0 | 2.1 | 9.0 | 5.8 | |
| 95%可信区间% | −0.5 to 16.5 | −6.3 to 10.6 | 0.1 to 17.8 | −2.6 to 14.3 | |
| Age group: 18–35年 | |||||
| n# | 23 | 21 | 21 | 13 | 28 |
| Least squares mean±se% | 70.1±5.00 | 58.8±5.12 | 68.0±5.30 | 62.3±6.60 | 56.9±4.78 |
| CIS armversusarm 5 | |||||
| Difference % | 13.2 | 1.9 | 11.1 | 5.5 | |
| 95%可信区间% | 0.9–25.6 | −10.8 to 14.6 | −1.4 to 23.6 | −9.1 to 20.0 | |
| Age group: 36–48年 | |||||
| n# | 20 | 24 | 22 | 28 | 19 |
| Least squares mean±se% | 82.0±5.38 | 82.3±4.90 | 74.7±5.05 | 76.3±4.68 | 65.6±5.47 |
| CIS armversusarm 5 | |||||
| Difference % | 16.5 | 16.8 | 9.1 | 10.8 | |
| 95%可信区间% | 2.6–30.3 | 3.4–30.1 | −4.4 to 22.6 | −2.1 to 23.7 | |
| Age group: 49–58年 | |||||
| n# | 21 | 21 | 18 | 27 | 13 |
| Least squares mean±se% | 85.1±5.30 | 84.6±5.21 | 79.2±5.52 | 82.1±4.70 | 76.4±6.47 |
| CIS armversusarm 5 | |||||
| Difference % | 8.7 | 8.2 | 2.8 | 5.7 | |
| 95%可信区间% | −6.8 to 24.2 | −7.1 to 23.5 | −13.1 to 18.6 | −8.9 to 20.3 | |
| Age group: >58年 | |||||
| n# | 19 | 18 | 23 | 14 | 25 |
| Least squares mean±se% | 88.0±5.56 | 82.8±5.53 | 91.6±5.05 | 87.4±6.42 | 81.6±4.90 |
| CIS armversusarm 5 | |||||
| Difference % | 6.4 | 1.2 | 10.0 | 5.8 | |
| 95%可信区间% | −6.9 to 19.7 | −12.2 to 14.6 | −2.6 to 22.6 | −9.1 to 20.6 |
Arm 1: maintenance data to participants and HCPs; arm 2: maintenance data to participants; arm 3: maintenance and rescue data to participants and HCPs; arm 4: maintenance and rescue data to participants; arm 5: no feedback (control). CIS: connected inhaler system; CI: confidence interval; HCP: healthcare professional.#: over months 4–6, n included the number of participants with observed and imputed data.