Associations between maternal Mediterranean diet score during pregnancy and asthma, wheeze, eczema, hay fever and atopy in the offspring (n=8629)
| Subjects | Mediterranean diet score | ||||
| 4–7versus0–3 | p-value | Per-unit increase | p-趋势 | ||
| Asthma | 7634 | ||||
| Model 1# | 0.94 (0.81–1.09) | 0.41 | 0.97 (0.92–1.01) | 0.15 | |
| Model 2¶ | 1.03 (0.88–1.20) | 0.71 | 1.00 (0.95–1.05) | 0.93 | |
| Wheeze | 7719 | ||||
| Model 1# | 1.02 (0.88–1.19) | 0.80 | 1.01 (0.96–1.06) | 0.84 | |
| Model 2¶ | 1.04 (0.89–1.22) | 0.62 | 1.01 (0.96–1.07) | 0.63 | |
| Eczema | 7705 | ||||
| Model 1# | 1.13 (0.99–1.29) | 0.07 | 1.03 (0.99–1.07) | 0.18 | |
| Model 2¶ | 1.10 (0.96–1.26) | 0.18 | 1.01 (0.97–1.06) | 0.55 | |
| Hay fever | 7685 | ||||
| Model 1# | 1.00 (0.85–1.18) | 0.99 | 1.01 (0.96–1.07) | 0.72 | |
| Model 2¶ | 0.97 (0.81–1.15) | 0.69 | 1.00 (0.94 - -1.06) | 0.97 | |
| Atopy | 6078 | ||||
| Model 1# | 1.03 (0.90–1.17) | 0.66 | 1.03 (0.98 - -1.07) | 0.23 | |
| Model 2¶ | 0.94 (0.82–1.07) | 0.34 | 0.99 (0.95–1.04) | 0.81 | |
Data are presented as n or OR (95% CI), unless otherwise stated.#: controlling for energy intake;¶: controlling for energy intake, smoking, infections, supplements, antibiotics and paracetamol use during pregnancy; maternal educational level, housing tenure, financial difficulties, ethnicity, age, parity, history of atopic diseases, anxiety; sex of child, season of birth, multiple pregnancy, breastfeeding duration.