表1

Lung transplant (LT) recipient characteristics according to primary graft dysfunction grade 3 (PGD3) development in the first 72 h

No PGD3 PGD3 p-value
肝移植受者 39 31
Preoperative characteristics
 Age years 55±12 55±9 0.84
 Females 12 (31%) 17 (55%) 0.05
 BMI kg·m−2 26±8 27±5 0.66
 Aetiology 0.07
  Pulmonary fibrosis 9 (23%) 14 (45%)
  COPD 18 (46%) 14 (45%)
  Pulmonary hypertension 2 (5%) 2 (7%)
  Cystic fibrosis 6 (16%) 0 (0%)
  Others 4 (10%) 1 (3%)
 Haemoglobin g·dL−1 14±2 14±2 0.88
 Plasma protein level g·dL−1 7.4±0.7 7.3±0.7 0.44
Intraoperative characteristics
 Procedure type:
双边LT 25 (64%) 20 (65%) 1.00
 CPB use 4 (10%) 9 (29%) 0.06
 Blood product transfusion packs 2 (4%) 4 (6%) 0.18
 iNO use 13 (33%) 25 (81%) <0.01
  For hypoxaemia 1 (8%) 16 (64%) 0.01
  For PH 11 (84%) 19 (76%) 0.26
 Ischaemia time min 299±76.0 332±64.8 0.05
Postoperative characteristics
 ICU mortality 0 (0%) 5 (16%) 0.02
 Hospital mortality 0 (0%) 7 (23%) <0.01
 28-day mortality 0 (0%) 4 (13%) 0.03
 90-day mortality 0 (0%) 6 (19%) <0.01
 ICU LOS days 22±23 32±15 0.04
 MV length days 16±22 28±18 0.02
  • Data are presented as mean±sdunless otherwise stated. BMI: body mass index; COPD: chronic obstructive pulmonary disease; CPB: cardiopulmonary bypass; iNO: inhaled nitric oxide; PH: pulmonary hypertension; ICU: intensive care unit; LOS: length of stay; MV: mechanical ventilation.