TY - JOUR T1 -全球慢性咳嗽调查:增强的躯体感觉的表现反应JF -欧洲呼吸杂志》乔和J SP - 1149 LP - 1155欧元——10.1183/09031936.00217813六世- 44 - 5盟Morice Alyn h . AU -厕所,亚当·d . AU - Faruqi Shoaib盟——出生,萨伦德s . AU - McGarvey Lorcan AU -坎宁,布伦丹盟-史密斯,她答:非盟-帕克,肖恩·m . AU - Chung Kian风扇AU -赖,Kefang AU - Pavord,伊恩·d . AU - van den Berg 1月非盟-歌,Woo-Jung AU - Millqvist,伊娃盟,法雷尔Michael J. AU - Mazzone, Stuart B. AU - Dicpinigaitis, Peter AU -， Y1 - 2014/11/01 UR - //www.qdcxjkg.com/content/44/5/1149.abstract N2 -来自个别中心的报告表明女性慢性咳嗽占优势。女性对咳嗽反射的敏感度也更高。在这里，我们回顾了未选择转介到11个咳嗽诊所的年龄和性别。为了调查任何观察到的性别二态的原因，对正常志愿者的推定咳嗽中心进行了功能性磁共振成像分析。评估了连续出现慢性咳嗽的患者的人口学特征。在正常志愿者中进行辣椒素咳嗽挑战，以构建浓度-反应曲线。在反复吸入亚咳浓度的辣椒素期间，随后的功能性磁共振成像观察到了大脑内的激活区域，并确定了性别差异。10032例慢性咳嗽患者中，三分之二(6591)为女性(平均年龄55岁)。 The patient profile was largely uniform across centres. The most common age for presentation was 60–69 years. The maximum tolerable dose of inhaled capsaicin was lower in females; however, a significantly greater activation of the somatosensory cortex was observed. Patients presenting with chronic cough from diverse racial and geographic backgrounds have a strikingly homogeneous demographic profile, suggesting a distinct clinical entity. The preponderance of females may be explained by sex-related differences in the central processing of cough sensation. Chronic cough in specialist clinics have homogenous demographic profiles, suggesting single clinical entity http://ow.ly/zrNAa ER -