TY -的T1 -初级纤毛的敏感性ry dyskinesia detection by ciliary function analysis 100%? JF - European Respiratory Journal JO - Eur Respir J SP - 1159 LP - 1161 DO - 10.1183/09031936.00078713 VL - 42 IS - 4 AU - Boon, Mieke AU - Jorissen, Mark AU - Jaspers, Martine AU - Cuppens, Harry AU - De Boeck, Kris Y1 - 2013/10/01 UR - //www.qdcxjkg.com/content/42/4/1159.abstract N2 - To the Editor:We read with interest the article by Pifferi et al. [1] in the April issue of the European Respiratory Journal, describing a technique of soft computing analysis to increase the diagnostic accuracy of air liquid interface cultures for the diagnosis of primary ciliary dyskinesia (PCD).The diagnosis of PCD is indeed difficult, time-consuming and expensive [2, 3]. Extensive efforts have been made to increase the diagnostic accuracy of the available tests.We worry that the authors miscalculated the statistical parameters sensitivity and specificity. Sensitivity reflects the accuracy of a new test to detect an abnormal result in a disease state (true positives), compared to the results of the gold standard to diagnose the disease state [4]. It is calculated by the formula a/a+b, in which a is the number of true positives and b the number of false positives (table 1). Specificity, on the other hand, reflects the accuracy of the new test to diagnose a normal value, … ER -