PT - 杂志Au - Laroumagne，Sophie Au - Lepage，BenoîtAu - Hermant，Christophe Au - Plat，Gavin Au - Phelippeau，Michael Au - Bigay-Game，Laurence Au - Lozano，StéphanieAu - Guibert，Nicolas Au - Segonds，Christine Au - Mallard，ValérieAu - Augustin，Nathalie Au - Didier，Alain Au - Mazieres，Julien Ti - 肺癌患者的支气管殖民化：一项潜在研究助剂 - 10.1183 / 09031936.00062212 DP - 2013年7月01日 - 欧洲呼吸期刊PG- 220--229 VI - 42 IP - 1 4099 - //www.qdcxjkg.com/content/42/1/220.short 4100 - //www.qdcxjkg.com/content/42/1/220.full so - eur respir J2013 7月01日;42 - 肺癌患者经常报道AB - 支气管殖民化，对治疗管理和预后具有潜在影响。我们的目标是在诊断肺癌时潜在定义患者支气管殖民化的患病率和性质。210连续肺癌患者接受肺癌柔性支气管镜检查。分析细菌，分枝杆菌和真菌结肠的类型和频率与患者和肿瘤的特征相关。在48.1％的样品中发现了潜在的病原体：主要是革兰氏阴性杆菌大肠杆菌（8.1％），嗜血杆菌嗜血杆菌（4.3％）和肠杆菌SPP。（2.4％）;革兰氏阳性Cocci，葡萄球菌SPP。 (12.9%) and Streptococcus pneumoniae (3.3%); atypical mycobacteria (2.9%); Candida albicans (42.9%); and Aspergillus fumigatus (6.2%). Aged patients (p=0.02) with chronic obstructive pulmonary disease (p=0.008) were significantly more frequently colonised; however, tumour stage, atelectasis, bronchial stenosis and abnormalities of chest radiography were not associated with a higher rate of colonisation. Squamous cell carcinoma tended to be more frequently colonised than other histological subtypes. Airway colonisation was reported in almost half of patients presenting with lung cancer, mainly in fragile patients, and was significantly associated with worse survival (p=0.005). Analysing colonisation status of patients at the time of diagnosis may help improve the management of lung cancer.