@article {laroumagne220，作者= {laroumagne，sophie and lepage，beno {\^\ i} t和hermant，christophe and plat，Gavin和Phelippeau，Michael and Bigay-Game，Laurence，Laurence and Lozano，ST {\'e} Phanie}以及吉伯特（Guibert），尼古拉斯（Nicolas）和塞贡兹（Segonds），克里斯汀（Christine）和野鸭（Mallard），瓦尔（Val）{\'e} rie和奥古斯丁，纳塔莉（Nathalie）和迪迪埃（Didier），阿兰（Alain）和马西耶斯（Mazieres），朱利安（Julien），title = {肺癌患者的支气管殖民化{前瞻性研究}，体积=，体积= ={42}，number = {1}，页面= {220--229}，eNAG = {2013}，doi = {10.1183/09031936.00062212}，Publisher = {欧洲呼吸社会}，摘188bet官网地址要= {肺癌患者，对治疗管理和预后有潜在的影响。我们的目的是在诊断出肺癌时前瞻性地定义患者支气管定殖的患病率和性质。210例肺癌连续患者进行了针对肺癌的柔性支气管镜检查。分析了细菌，分枝杆菌和真菌定植的类型和频率，并与患者{\ textquoteright}和肿瘤{\ textquoteright}特征相关。在48.1％的样品中发现了潜在的病原体：主要是革兰氏阴性芽孢杆菌大肠杆菌（8.1 \％），流感嗜血杆菌（4.3 \％）和肠杆菌属。（2.4 \％）;革兰氏阳性球菌，葡萄球菌属。 (12.9\%) and Streptococcus pneumoniae (3.3\%); atypical mycobacteria (2.9\%); Candida albicans (42.9\%); and Aspergillus fumigatus (6.2\%). Aged patients (p=0.02) with chronic obstructive pulmonary disease (p=0.008) were significantly more frequently colonised; however, tumour stage, atelectasis, bronchial stenosis and abnormalities of chest radiography were not associated with a higher rate of colonisation. Squamous cell carcinoma tended to be more frequently colonised than other histological subtypes. Airway colonisation was reported in almost half of patients presenting with lung cancer, mainly in fragile patients, and was significantly associated with worse survival (p=0.005). Analysing colonisation status of patients at the time of diagnosis may help improve the management of lung cancer.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/42/1/220}, eprint = {//www.qdcxjkg.com/content/42/1/220.full.pdf}, journal = {European Respiratory Journal} }