TY -的T1 -神秘的心脏病留在scleroderma-pulmonary高血压JF -欧洲呼吸杂志》乔和J SP - 1083 LP - 1091欧元——10.1183/09031936.00091212六世- 42 - 4非盟-福克斯,本杰明·d . AU - Shimony Avi盟——Langleben大卫AU -赫希,Andrew AU - Rudski劳伦斯AU -施莱辛格,Robert AU - Eisenberg, Mark J. AU - Joyal, Dominique AU - Hudson, Marie AU - Boutet, Kim AU - Serban, Alexandrina AU - Masetto, Ariel AU - Baron，Murray Y1 - 2013/10/01 UR - //www.qdcxjkg.com/content/42/4/1083.abstract N2 -我们的研究旨在确定硬皮病和肺动脉高压患者隐匿性左心疾病的患病率。对于肺动脉高压患者(平均肺动脉压(mean pulmonary artery pressure, PAP)≥25 mmHg)，分别以肺动脉楔压(pulmonary artery wedge pressure, PAWP)小于或大于15 mmHg来区分毛细血管前期和后肺动脉高压。我们对107例硬皮病患者进行了回顾性分析。所有疑似肺动脉高压的患者在液体刺激前后均常规行右或左心导管置管并测量左室舒张末期压(LVEDP)。我们提取了人口统计学、血流动力学和超声心动图数据。患者被分为四组:血流动力学正常(平均PAP< 25mmhg);肺动脉静脉高压(PVH)(平均PAP≥25 mmHg, PAWP>15 mmHg);隐匿性PVH(平均PAP≥25mmhg, PAWP≤15mmhg, LVEDP>液体刺激前后15mmhg); and pulmonary arterial hypertension (PAH) (mean PAP≥25 mmHg, PAWP≤15 mmHg and LVEDP≤15 mmHg before or after fluid challenge). 53 out of 107 patients had pulmonary hypertension. Based on the PAWP-based definition, 29 out of 53 had PAH and 24 out of 53 had PVH. After considering the resting and post-fluid-challenge LVEDP, 11 PAH patients were reclassified as occult PVH. The occult PVH group was haemodynamically, echocardiographically and demographically closer to the PVH group than the PAH group. PVH had high prevalence in our scleroderma-pulmonary hypertension population. Distinguishing PAH from PVH with only PAWP may result in some PVH patients being misclassified as having PAH. Left heart catheterisation with saline infusion helps in the diagnosis of suspected PH in scleroderma http://ow.ly/mxuXE ER -