TY - T1的早期模式气喘儿童哮喘和nonasthmatic JF -欧洲呼吸杂志》乔和J SP - 1020 LP - 1028欧元——10.1183/09031936.00148712六世- 42 - 4盟诺Garcinuno阿尔弗雷多AU -莫拉Gandarillas,Isabel AU - the SLAM Study Group Y1 - 2013/10/01 UR - //www.qdcxjkg.com/content/42/4/1020.abstract N2 -本研究的目的是描述哮喘患儿和非哮喘患儿在出生后36个月的喘息时间模式。并确定哮喘发病率中是否存在与哮喘相关的断点。使用了从出生到6岁随访儿童的历史队列数据(SLAM队列)。36个月前的喘息发作和6岁时的哮喘发作均由医生记录。计算哮喘的月平均发病率和率比。建立连接点回归模型以识别喘息风险中的断点。3739名儿童获得了完整的信息。哮喘患儿在前36个月比非哮喘患儿更易出现喘息(比率为2.62,95%可信区间为1.81-3.78)。由于哮喘儿童的发病率持续高企，在最初的几个月里差异是明显的，并在之后稳步增加。 No breakpoint in the rate ratio could be identified. Asthmatic children exhibited a one-phase curve of incidence and nonasthmatic children exhibited a two-phase curve. However, children with allergic asthma also displayed a two-phase curve. There is no identifiable breakpoint during the first 36 months of life at which the incidence of wheezing in asthmatic children begins to stand out. Increased wheezing in asthmatic children from birth; different progression patterns for allergic and nonallergic asthma http://ow.ly/lo9Yk ER -