TY -的T1 -体外膜肺氧合in a nonintubated patient with acute respiratory distress syndrome JF - European Respiratory Journal JO - Eur Respir J SP - 1296 LP - 1298 DO - 10.1183/09031936.00076912 VL - 40 IS - 5 AU - Wiesner, Olaf AU - Hadem, Johannes AU - Sommer, Wiebke AU - Kühn, Christian AU - Welte, Tobias AU - Hoeper, Marius M. Y1 - 2012/11/01 UR - //www.qdcxjkg.com/content/40/5/1296.abstract N2 - To the Editors:Endotracheal intubation and mechanical ventilation are mainstays in the management of patients with acute respiratory distress syndrome (ARDS), but this treatment strategy exposes the patient to several risks and complications. A small number of ARDS patients can be treated with noninvasive ventilation and these patients have less ventilator-associated pneumonia and a lower mortality rate [1]. However, failure to improve oxygenation with noninvasive ventilation indicates the need for endotracheal intubation [1].In patients with severe respiratory failure, extracorporeal membrane oxygenation (ECMO) is increasingly being used on top of mechanical ventilation to facilitate oxygenation and protective ventilation [2]. A novel concept is the use of ECMO in awake, spontaneously breathing patients to avoid the complications of invasive ventilation. So far, “awake ECMO” has been used predominantly in patients with end-stage lung disease as bridge to lung transplantation [3, 4]. The use of awake ECMO as … ER -