ty -jour t1-欧盟和欧洲经济区国家的TB和MDR/XDR -TB:管理还是管理不善?JF-欧洲呼吸杂志JO -EUR RESSIR J SP -619 LP -625 DO -10.1183/09031936.00170411 VL -39 IS -3 AU -MIGLIORI,G.B.au -sotgiu,G。au -d'Ambrosio,L。au -centis,R。au -au -lange,C。au -Bothamley,G。au -au -cirillo,D.M。Au -de Lorenzo,S。Au -Guenther,G。Au -Kliiman,K。Au -Muetterlein,R.Au -au -au -spinu,V。au -Villar,M.Au -au -au -Zellweger,J.P. Au -Sandgren,A.Au -au -au -au -au -au -au -au -au -au -au-Huitric,E。Au -Manissero,D。Y1-2012/03/01 Ur -http://www.qdcxjkg.com/content/39/3/3/619.Abstract N2-尽管人们对新兴药物的认识越来越高抗性分枝杆菌结核病,不适当的结核病(TB)病例管理的程度,即使在欧洲也可能被低估。我们使用目的性,标准化的调查工具,特别关注欧盟/欧洲经济区国家的结核病案例管理,特别关注多药耐药性(MDR)和广泛耐药(XDR)-TB。五个国家的国家参考中心在欧洲的五个国家 /地区代表了不同地理,社会经济和流行病学模式。在五个国家/地区中,每个国家/地区审查了40个连续的原始临床结核病病例记录(30个MDR/XDR-TB病例)。与先前商定和确定的国际标准相比,通过调查工具记录了这些发现。在以下领域中观察到与国际结核病护理标准的偏差:监视(没有有关患者预后的信息); infection control (lack of respiratory isolation rooms/procedures and negative-pressure ventilation rooms); clinical management of TB, MDR-TB and HIV co-infection (inadequate bacteriological diagnosis, regimen selection and treatment duration); laboratory support; and diagnostic/treatment algorithms. Gaps between present international standards of care and the management of MDR/XDR-TB patients were identified. Training, increased awareness, promotion of standards and allocation of appropriate resources are necessary to ensure appropriate care and management as well as to prevent further emergence of drug resistance. ER -