RT期刊文章SR电子T1肺部导管诊断为镰状细胞病JF欧洲呼吸系统杂志JO EUR RESSIR J FD欧洲呼吸学会SP 112 OP 118 DO 10.1183/09031936.00134410 VO 39 IS 1 A1 FONSECA，G.H.H.188bet官网地址A1 Souza，R。A1Salemi，V.M.C。A1 Jardim，C.V.P。A1 Gualandro，S.F.M.YR 2012 UL //www.qdcxjkg.com/content/39/1/112.abstract ab最近的研究已经认识到肺部细胞病（SCD）中肺动脉高压（pH）的重要性。这项研究的目的是确定pH值及其在SCD患者中的患病率和预后影响。80例SCD患者接受了基线临床评估，实验室测试，6分钟步行测试（6MWTS）和超声心动图。通过右心导管插入术（RHC）进一步评估了≥2.5m·S -1峰值三尖峰型射流速度（TRV）的患者，以确保诊断pH值。我们的研究证明了超声心动图中TRV升高患者的40％患病率。RHC（在32名患者中25例中进行）证实了所有患者的10％（95％CI 3.4-16.5％），毛细血管后pH值为6.25％（95％CI 0.95-11.55％）和前毛细血管后的患病率为pH。- 毛细血管pH为3.75％（95％CI -0.4-7.9％）。 Patients with PH were older, had worse performance in 6MWTs, and more pronounced anaemia, haemolysis and renal dysfunction. Survival was shorter in patients with PH. Our study reinforced the use of echocardiography as a screening tool for PH in SCD and the mandatory role of RHC for proper diagnosis. Our findings confirmed the prognostic significance of PH in SCD as its association to pronounced haemolytic profile.