@article {fonseca112，作者= {fonseca，g.h.h。和R. Souza和V.M.C. Salemi和C.V.P. Jardim和gualandro，s.f.m.}，title = {通过镰状细胞病中的右心导管诊断}，体积= {39}，数字= {1}，pages = {112---118}，年= {2012}，doi = {2012}，doi= {10.1183/09031936.00134410}，出版商= {欧洲呼吸社会}，188bet官网地址摘要= {最近的研究已经认识到镰状细胞病（SCD）的肺高血压（pH）的重要性。这项研究的目的是确定pH值及其在SCD患者中的患病率和预后影响。80例SCD患者接受了基线临床评估，实验室测试，6分钟步行测试（6MWTS）和超声心动图。通过右心导管插入术（RHC）进一步评估了> = 2.5 m {\ textperiodeDcentered} S-1的峰值三尖端反流速度（TRV）的患者，以确保诊断pH。我们的研究证明了超声心动图中TRV升高的患者的患病率为40％。RHC（在32名患者中25例中进行）确认10 \％（95 \％CI 3.4 {\ textendash} 16.5 \％）在所有患者中，患病率为6.25 \％（95 \％）（95 \％） CI 0.95{\textendash}11.55\%) and pre-capillary PH of 3.75\% (95\% CI -0.4{\textendash}7.9\%). Patients with PH were older, had worse performance in 6MWTs, and more pronounced anaemia, haemolysis and renal dysfunction. Survival was shorter in patients with PH. Our study reinforced the use of echocardiography as a screening tool for PH in SCD and the mandatory role of RHC for proper diagnosis. Our findings confirmed the prognostic significance of PH in SCD as its association to pronounced haemolytic profile.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/39/1/112}, eprint = {//www.qdcxjkg.com/content/39/1/112.full.pdf}, journal = {European Respiratory Journal} }