TY - T1的回廊中氧气间隙lung disease JF - European Respiratory Journal JO - Eur Respir J SP - 987 LP - 990 DO - 10.1183/09031936.00190710 VL - 38 IS - 4 AU - Visca, D. AU - Montgomery, A. AU - de Lauretis, A. AU - Sestini, P. AU - Soteriou, H. AU - Maher, T.M. AU - Wells, A.U. AU - Renzoni, E.A. Y1 - 2011/10/01 UR - //www.qdcxjkg.com/content/38/4/987.abstract N2 - To the Editors:Interstitial lung diseases (ILDs) are often associated with significant oxygen desaturation on exercise, resulting in exercise limitation, exertional dyspnoea and reduced quality of life. However, surprisingly few data are available on ambulatory oxygen in ILD. The 6-min walk test (6MWT), a self-paced test performed according to standardised protocols, has been shown to be highly reproducible in ILD patients [1], and is felt to be more sensitive than a cycle ergometer test in assessing oxygen requirements [2].We present a retrospective assessment of the effects of ambulatory oxygen on 6MWT performance in a group of patients with fibrotic ILD seen at the Interstitial Lung Disease Unit, Royal Brompton Hospital, London, UK. The 6MWT was performed following a standardised protocol [3, 4]; patients were asked to perform the 6MWT at their habitual walking pace and were allowed to stop if they experienced unacceptable symptoms of dyspnoea and/or fatigue; standardised encouragement to restart the test was given at regular intervals.A review of the clinical records of ILD patients seen at the Royal Brompton Hospital, from November 2007 to January 2010, identified 52 ILD patients with a fall in arterial oxygen saturation (Sa,O2) ≤88% at the end of a baseline 6MWT, who had consented to a second test on ambulatory oxygen during the same session, as part of their routine clinical assessment. All 6MWTs were performed on the same measured corridor and were supervised by the same experienced oxygen technician (A. Montgomery), with a minimum rest period of 20 min between tests. Measurements included 6-min walk distance (6MWD), Sa,O2, heart rate, and modified Borg dyspnoea score (range 1–10) assessed immediately before and after each 6MWT [5]. Recovery times to baseline Sa,O2, heart rate, and Borg score were also measured … ER -