TY -的T1 -体重指数之间的关系,年龄和打鼾和睡眠呼吸暂停患者的上呼吸道测量JF -欧洲呼吸杂志》乔和J SP - 1801 LP - 1809欧元六世- 9 - 9 AU - Mayer, P盟——Pepin杰盟-贝特加,G盟——Veale D盟——近期,G盟——Deschaux C AU -莱维,P Y1 - 1999.09 - 01 UR - //www.qdcxjkg.com/content/9/9/1801.abstract N2 -上呼吸道成像已报道有或无阻塞性睡眠呼吸暂停(OSA)的打鼾者出现解剖性咽部和颅面异常。然而，患者的年龄和体重对这些异常的影响仍有待确定。因此，本研究的目的是评估在有或没有OSA的大量打鼾人群中，身体质量指数(BMI)、年龄和上呼吸道形态之间的关系。140例患者接受了可能的睡眠相关呼吸障碍的评估，并进行了完整的多导睡眠描记仪、头颅测量仪和上呼吸道计算机断层扫描。在整个人群中，OSA患者比打鼾者有更多的上呼吸道异常。但在BMI和年龄细分时，只有较瘦或较年轻的OSA患者的上呼吸道解剖结构与打鼾者有显著差异。无论是OSA患者还是打鼾者，口咽和下咽的形状都随BMI发生显著变化，BMI最高组的口咽和下咽形状更球形，主要原因是横轴下降。另一方面，老年患者(>63岁)，无论是打鼾者还是呼吸暂停者，在所有咽部水平上气道都比最年轻的一组患者(< 52 yrs). For the total group of patients, upper airway variables explained 26% of the variance in apnoea/hypopnoea index (AHI), whereas in lean (BMI < 27 kg.m-2) or youngest (age < 52 yrs) subjects upper airway variables explained, respectively 69 and 55% of the variance in AHI. In conclusion, in lean or young subjects, upper airway abnormalities explain a major part of the variance in apnoea/hypopnoea index and are likely to play an important physiopathogenic role. This study also suggests that the shape of the pharyngeal lumen in awake subjects is more dependent on body mass index than on the presence of obstructive sleep apnoea. Further investigation looking at upper airway imaging for surgical selection in obstructive sleep apnoea should focus on lean and young patients. ER -