@article {teschler680，作者= {Teschler，H和Thompson，AB和Dollenkamp，R和Konietzko，N和Konietzko，N和Costabel，u}，title = {putum}中的石棉机构的相关性}，pages = {680--686}，年= {1996}，出版商= {欧洲呼吸社会}，Abstra188bet官网地址ct = {{在具有职业石棉曝光的个体中的石棉体（ABS）的存在已得到充分证明。这项研究的目的是确定它们的临床相关性，与支气管肺泡灌注（BAL）和肺组织中的AB浓度相比。在有据可查的石棉病史（n = 93）或BAL流体分析的ABS呈阳性（n = 42）的情况下，包括受试者。具有良好记录的AB暴露历史的受试者分为三组：重（第1组，n = 29）；中度（第2组，n = 31）;或偶尔暴露（第3组，n = 33）。所有受试者均可获得BAL液，以及21名受试者的肺组织。为了评估可变性，在第2、7、14、30和90天收集了10个痰液阳性受试者。在试样消化的膜过滤后通过光学显微镜确定ABS。第1组（2.4 +/- 5.5 ab.ml-1）中的平均痰液AB含量最高，第2组（0.2 +/- 0.3 AB.ML-1）较低，第3组最低（0.1 +/- 0.1 AB.mL-1) suggesting a correlation with cumulative exposure. However, many negative sputum samples were noted, when BAL specimens were positive. The AB content of sputum and BAL specimens did not correlate. ABs were found in sputum of all subjects with a tissue content of \> 1,000 AB-cm-3, but in none with contents of \< 1,000 AB-cm-3. Substantial variability of ABs was found in the five sequentially collected sputa of 10 initially positive patients (coefficient of variation 28-93\%), but only two false negatives were found in these 50 samples. Thus, sputum analysis for asbestos bodies is an insensitive method for assessing the lung asbestos burden, much less sensitive than bronchoalveolar lavage fluid analysis. However, a sputum sample positive for asbestos bodies is suggestive of a high lung asbestos burden.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/9/4/680}, eprint = {//www.qdcxjkg.com/content/9/4/680.full.pdf}, journal = {European Respiratory Journal} }